Recent Insights into Emerging Coronavirus: SARS-CoV-2

Zifang Shang, Siew Yin Chan, William J. Liu, Peng Li, Wei Huang

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations

Abstract

The SARS-CoV-2 outbreak that emerged at the end of 2019 has affected more than 58 million people with more than 1.38 million deaths and has had an incalculable impact on the world. Extensive prevention and treatment measures have been implemented since the pandemic. In this Review, we summarize current understanding on the source, transmission characteristics, and pathogenic mechanism of SARS-CoV-2. We also detail the recent development of diagnostic methods and potential treatment strategies of COVID-19 with focus on the ongoing clinical trials of antibodies, vaccines, and inhibitors for combating the emerging coronavirus.

Original languageEnglish
Pages (from-to)1369-1388
Number of pages20
JournalACS Infectious Diseases
Volume7
Issue number6
DOIs
StatePublished - 11 Jun 2021

Keywords

  • antibody
  • COVID-19
  • diagnosis
  • inhibitor
  • pandemic
  • pathogenesis
  • SARS-CoV-2
  • therapy
  • transmission
  • vaccine

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