TY - JOUR
T1 - Recent Advances in Nanomaterial-based Luminescent ATP Sensors
AU - Zhou, Xiaomeng
AU - Shang, Li
N1 - Publisher Copyright:
© 2022 Bentham Science Publishers.
PY - 2022/7
Y1 - 2022/7
N2 - Adenosine 5'-triphosphate (ATP) plays a significant role in biological processes and the ATP level is closely associated with many diseases. In order to detect ATP in live cells, tissues, and body fluids with high sensitivity and selectivity, researchers have developed various sensing strategies. Particularly, owing to the distinct physicochemical properties of nanomaterials and the high sensitivity of fluorescence, a lot of efforts have been devoted to developing nanomaterials-based approaches for fluorescent ATP sensing in recent years. In this review, we focus on the current development of nanomaterial-based fluorescent ATP sensors and discuss the sensing mechanisms in detail. The advantages and disadvantages of ATP sensing using different kinds of nanomaterials, including carbon nanomaterials, metal nanoparticles, semiconductor quantum dots, metal-organic frameworks, and up-conversion nanoparticles have been thoroughly compared and discussed. Finally, current challenges and future prospects in this field are examined.
AB - Adenosine 5'-triphosphate (ATP) plays a significant role in biological processes and the ATP level is closely associated with many diseases. In order to detect ATP in live cells, tissues, and body fluids with high sensitivity and selectivity, researchers have developed various sensing strategies. Particularly, owing to the distinct physicochemical properties of nanomaterials and the high sensitivity of fluorescence, a lot of efforts have been devoted to developing nanomaterials-based approaches for fluorescent ATP sensing in recent years. In this review, we focus on the current development of nanomaterial-based fluorescent ATP sensors and discuss the sensing mechanisms in detail. The advantages and disadvantages of ATP sensing using different kinds of nanomaterials, including carbon nanomaterials, metal nanoparticles, semiconductor quantum dots, metal-organic frameworks, and up-conversion nanoparticles have been thoroughly compared and discussed. Finally, current challenges and future prospects in this field are examined.
KW - adenosine triphosphate
KW - aptamer
KW - biosensors
KW - cellular processes
KW - fluorescence
KW - Nanomaterials
UR - http://www.scopus.com/inward/record.url?scp=85131192038&partnerID=8YFLogxK
U2 - 10.2174/1573411017666210909121746
DO - 10.2174/1573411017666210909121746
M3 - 文章
AN - SCOPUS:85131192038
SN - 1573-4110
VL - 18
SP - 677
EP - 688
JO - Current Analytical Chemistry
JF - Current Analytical Chemistry
IS - 6
ER -