Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography

Xiaojun Yu; Razina Z. Seeni; Linbo Liu; Chenjie Xu

doi:10.1109/CLEOPR.2017.8118613

Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography

Xiaojun Yu, Razina Z. Seeni, Linbo Liu, Chenjie Xu

School of Automation

Nanyang Technological University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

We report on noninvasive characterization of MNs' real-Time swelling property in mice-skin using a lab-built microoptical coherence tomography (μOCT). Specifically, we propose to encapsulate the iron-oxide (Fe₃O₄) nanoparticles into polymeric MNs as contrast agent to enhance OCT image contrast, and then evaluate its influences on contrast enhancement quantitatively. The MNs' real-Time temporal swelling behaviors in miceskin are recorded and analyzed. This is the first quantitative study on MNs' temporal swelling property in biological tissue using μOCT.

Original language	English
Title of host publication	2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	1-2
Number of pages	2
ISBN (Electronic)	9781509062904
DOIs	https://doi.org/10.1109/CLEOPR.2017.8118613
State	Published - 22 Nov 2017
Event	2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017 - Singapore, Singapore Duration: 31 Jul 2017 → 4 Aug 2017

Publication series

Name	2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017
Volume	2017-January

Conference

Conference	2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017
Country/Territory	Singapore
City	Singapore
Period	31/07/17 → 4/08/17

Keywords

Contrast agent
Iron oxide nanoparticles
Microneedles
OCT
Swelling imaging

Access to Document

10.1109/CLEOPR.2017.8118613

Cite this

Yu, X., Seeni, R. Z., Liu, L., & Xu, C. (2017). Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography. In 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017 (pp. 1-2). (2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017; Vol. 2017-January). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CLEOPR.2017.8118613

Yu, Xiaojun ; Seeni, Razina Z. ; Liu, Linbo et al. / Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography. 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 1-2 (2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017).

@inproceedings{92ae9b1fdc034aab8732e4e2ad8bdae2,

title = "Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography",

abstract = "We report on noninvasive characterization of MNs' real-Time swelling property in mice-skin using a lab-built microoptical coherence tomography (μOCT). Specifically, we propose to encapsulate the iron-oxide (Fe3O4) nanoparticles into polymeric MNs as contrast agent to enhance OCT image contrast, and then evaluate its influences on contrast enhancement quantitatively. The MNs' real-Time temporal swelling behaviors in miceskin are recorded and analyzed. This is the first quantitative study on MNs' temporal swelling property in biological tissue using μOCT.",

keywords = "Contrast agent, Iron oxide nanoparticles, Microneedles, OCT, Swelling imaging",

author = "Xiaojun Yu and Seeni, {Razina Z.} and Linbo Liu and Chenjie Xu",

year = "2017",

month = nov,

day = "22",

doi = "10.1109/CLEOPR.2017.8118613",

language = "英语",

series = "2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "1--2",

booktitle = "2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017",

}

Yu, X, Seeni, RZ, Liu, L & Xu, C 2017, Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography. in 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017. 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017, vol. 2017-January, Institute of Electrical and Electronics Engineers Inc., pp. 1-2, 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017, Singapore, Singapore, 31/07/17. https://doi.org/10.1109/CLEOPR.2017.8118613

Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography. / Yu, Xiaojun; Seeni, Razina Z.; Liu, Linbo et al.
2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017. Institute of Electrical and Electronics Engineers Inc., 2017. p. 1-2 (2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017; Vol. 2017-January).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography

AU - Yu, Xiaojun

AU - Seeni, Razina Z.

AU - Liu, Linbo

AU - Xu, Chenjie

PY - 2017/11/22

Y1 - 2017/11/22

N2 - We report on noninvasive characterization of MNs' real-Time swelling property in mice-skin using a lab-built microoptical coherence tomography (μOCT). Specifically, we propose to encapsulate the iron-oxide (Fe3O4) nanoparticles into polymeric MNs as contrast agent to enhance OCT image contrast, and then evaluate its influences on contrast enhancement quantitatively. The MNs' real-Time temporal swelling behaviors in miceskin are recorded and analyzed. This is the first quantitative study on MNs' temporal swelling property in biological tissue using μOCT.

AB - We report on noninvasive characterization of MNs' real-Time swelling property in mice-skin using a lab-built microoptical coherence tomography (μOCT). Specifically, we propose to encapsulate the iron-oxide (Fe3O4) nanoparticles into polymeric MNs as contrast agent to enhance OCT image contrast, and then evaluate its influences on contrast enhancement quantitatively. The MNs' real-Time temporal swelling behaviors in miceskin are recorded and analyzed. This is the first quantitative study on MNs' temporal swelling property in biological tissue using μOCT.

KW - Contrast agent

KW - Iron oxide nanoparticles

KW - Microneedles

KW - OCT

KW - Swelling imaging

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U2 - 10.1109/CLEOPR.2017.8118613

DO - 10.1109/CLEOPR.2017.8118613

M3 - 会议稿件

AN - SCOPUS:85044145424

T3 - 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017

SP - 1

EP - 2

BT - 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017

Y2 - 31 July 2017 through 4 August 2017

ER -

Yu X, Seeni RZ, Liu L, Xu C. Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography. In 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017. Institute of Electrical and Electronics Engineers Inc. 2017. p. 1-2. (2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017). doi: 10.1109/CLEOPR.2017.8118613

Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography

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