TY - JOUR
T1 - Phytochemicals, pharmacology, clinical application, patents, and products of Amomi fructus
AU - Suo, Sizhuo
AU - Lai, Yunfeng
AU - Li, Meng
AU - Song, Qirui
AU - Cai, Jing
AU - Zhao, Jing
AU - Yang, Qing
AU - Ung, Carolina Oi Lam
AU - Hu, Hao
N1 - Publisher Copyright:
© 2018 Elsevier Ltd
PY - 2018/9
Y1 - 2018/9
N2 - Amomi fructus (A. fructus) (Sharen) is a well-known traditional Chinese medicine widely used to treat gastrointestinal diseases. It has high medical and economic values, which have been confirmed both in vitro and in vivo studies. This review highlights the phytochemicals, pharmacology, clinical application, patents, and products of A. fructus. More than 100 phytochemicals have been isolated and identified from A. fructus, mainly including volatile oils, saponins, flavonoids, organic acids, inorganic ingredients, and polysaccharides. The main pharmacology of gastrointestinal protection, anti-inflammatory activity, analgesic activity, antidiarrheal activity, antibacterial activity, anti-microbial activity and hypoglycemic activity have been confirmed. The main clinical applications include functional digestion disorder, gastritis, helicobacter pylori infection in children and treatment of mastitis. There are 23 patents and 405 different drug products of A. fructus.
AB - Amomi fructus (A. fructus) (Sharen) is a well-known traditional Chinese medicine widely used to treat gastrointestinal diseases. It has high medical and economic values, which have been confirmed both in vitro and in vivo studies. This review highlights the phytochemicals, pharmacology, clinical application, patents, and products of A. fructus. More than 100 phytochemicals have been isolated and identified from A. fructus, mainly including volatile oils, saponins, flavonoids, organic acids, inorganic ingredients, and polysaccharides. The main pharmacology of gastrointestinal protection, anti-inflammatory activity, analgesic activity, antidiarrheal activity, antibacterial activity, anti-microbial activity and hypoglycemic activity have been confirmed. The main clinical applications include functional digestion disorder, gastritis, helicobacter pylori infection in children and treatment of mastitis. There are 23 patents and 405 different drug products of A. fructus.
KW - Amomi fructus
KW - Clinical application
KW - Patents and products
KW - Pharmacology
KW - Phytochemicals
UR - http://www.scopus.com/inward/record.url?scp=85047567497&partnerID=8YFLogxK
U2 - 10.1016/j.fct.2018.05.051
DO - 10.1016/j.fct.2018.05.051
M3 - 文章
C2 - 29802946
AN - SCOPUS:85047567497
SN - 0278-6915
VL - 119
SP - 31
EP - 36
JO - Food and Chemical Toxicology
JF - Food and Chemical Toxicology
ER -