MRI magnetic compatible electrical neural interface: From materials to application

Neural electrical interfaces are important tools for local neural stimulation and recording, which potentially have wide application in the diagnosis and treatment of neural diseases, as well as in the transmission of neural activity for brain-computer interface (BCI) systems. At the same time, magnetic resonance imaging (MRI) is one of the effective and non-invasive techniques for recording whole-brain signals, providing details of brain structures and also activation pattern maps. Simultaneous recording of extracellular neural signals and MRI combines two expressions of the same neural activity and is believed to be of great importance for the understanding of brain function. However, this combination makes requests on the magnetic and electronic performance of neural interface devices. MRI-compatibility refers here to a technological approach to simultaneous MRI and electrode recording or stimulation without artifacts in imaging. Trade-offs between materials magnetic susceptibility selection and electrical function should be considered. Herein, prominent trends in selecting materials of suitable magnetic properties are analyzed and material design, function and application of neural interfaces are outlined together with the remaining challenge to fabricate MRI-compatible neural interface.