Microstructure and cytotoxicity of Al2O3-ZrO2 eutectic bioceramics with high mechanical properties prepared by laser floating zone melting

Guangrao Fan, Haijun Su, Jun Zhang, Min Guo, Hui Yang, Haifang Liu, Enyuan Wang, Lin Liu, Hengzhi Fu

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Developing new generation of strong, tough and stable bioceramics used in dental filed has been highly desired for attaining the clinical requirement of secure and reliable therapy. In this paper, a novel Al2O3-ZrO2 eutectic bioceramics with nearly fully density and extremely aesthetic luster was in-situ prepared by innovative laser floating zone melting (LFZM) method. The influence of solidification rates on microstructure evolution, mechanical properties and cytotoxicity was investigated. The eutectic bioceramics displayed a special three dimensional interpenetrating microstructure evolving with increasing the solidification rate. The eutectic colony structure occurred when solidification rate overpassed 8 µm/s, and lamellar spacing was below 1 µm when solidification rate exceeded 30 µm/s. The eutectic bioceramics solidified at 100 µm/s exhibited optimal mechanical properties with an average hardness of 16.53 GPa, fracture toughness of 6.5 MPa m1/2 and flexural strength of 1.37 GPa. The cytotoxicity of Al2O3-ZrO2 eutectic bioceramics was evaluated by MTT methods according to ISO 10993-5 standard. Non-cytotoxic behavior was detected for the eutectic bioceramics, indicating this eutectic bioceramic could be used as promising dental restoration material.

Original languageEnglish
Pages (from-to)17978-17985
Number of pages8
JournalCeramics International
Volume44
Issue number15
DOIs
StatePublished - 15 Oct 2018

Keywords

  • AlO-ZrO eutectic bioceramics
  • Cytotoxicity
  • Dental material
  • Laser floating zone melting
  • Mechanical property

Fingerprint

Dive into the research topics of 'Microstructure and cytotoxicity of Al2O3-ZrO2 eutectic bioceramics with high mechanical properties prepared by laser floating zone melting'. Together they form a unique fingerprint.

Cite this