Lewis acid catalyzed intramolecular [3+2] cross-cycloaddition of donor-acceptor cyclopropanes with carbonyls: A general strategy for the construction of acetal[n.2.1] skeletons

Siyang Xing; Yan Li; Zhen Li; Chang Liu; Jun Ren; Zhongwen Wang

doi:10.1002/anie.201106368

Lewis acid catalyzed intramolecular [3+2] cross-cycloaddition of donor-acceptor cyclopropanes with carbonyls: A general strategy for the construction of acetal[n.2.1] skeletons

Siyang Xing, Yan Li, Zhen Li, Chang Liu, Jun Ren, Zhongwen Wang

Nankai University

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Abstract

Build a bridge: The first catalytic intramolecular [3+2] cycloaddition of monodonor-monoacceptor cyclopropanes (see scheme) provides a general and efficient strategy for construction of structurally diverse acetal[n.2.1] and 1,4-dioxygen-substituted cyclic skeletons, which are widely distributed in biologically important natural products.

Original language	English
Pages (from-to)	12605-12609
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	52
DOIs	https://doi.org/10.1002/anie.201106368
State	Published - 23 Dec 2011
Externally published	Yes

Keywords

Lewis acids
cycloaddition
cyclopropane
medium-sized rings
natural products

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10.1002/anie.201106368

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abstract = "Build a bridge: The first catalytic intramolecular [3+2] cycloaddition of monodonor-monoacceptor cyclopropanes (see scheme) provides a general and efficient strategy for construction of structurally diverse acetal[n.2.1] and 1,4-dioxygen-substituted cyclic skeletons, which are widely distributed in biologically important natural products.",

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author = "Siyang Xing and Yan Li and Zhen Li and Chang Liu and Jun Ren and Zhongwen Wang",

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Lewis acid catalyzed intramolecular [3+2] cross-cycloaddition of donor-acceptor cyclopropanes with carbonyls: A general strategy for the construction of acetal[n.2.1] skeletons. / Xing, Siyang; Li, Yan; Li, Zhen et al.
In: Angewandte Chemie - International Edition, Vol. 50, No. 52, 23.12.2011, p. 12605-12609.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Lewis acid catalyzed intramolecular [3+2] cross-cycloaddition of donor-acceptor cyclopropanes with carbonyls

T2 - A general strategy for the construction of acetal[n.2.1] skeletons

AU - Xing, Siyang

AU - Li, Yan

AU - Li, Zhen

AU - Liu, Chang

AU - Ren, Jun

AU - Wang, Zhongwen

PY - 2011/12/23

Y1 - 2011/12/23

N2 - Build a bridge: The first catalytic intramolecular [3+2] cycloaddition of monodonor-monoacceptor cyclopropanes (see scheme) provides a general and efficient strategy for construction of structurally diverse acetal[n.2.1] and 1,4-dioxygen-substituted cyclic skeletons, which are widely distributed in biologically important natural products.

AB - Build a bridge: The first catalytic intramolecular [3+2] cycloaddition of monodonor-monoacceptor cyclopropanes (see scheme) provides a general and efficient strategy for construction of structurally diverse acetal[n.2.1] and 1,4-dioxygen-substituted cyclic skeletons, which are widely distributed in biologically important natural products.

KW - Lewis acids

KW - cycloaddition

KW - cyclopropane

KW - medium-sized rings

KW - natural products

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DO - 10.1002/anie.201106368

M3 - 文章

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JO - Angewandte Chemie - International Edition

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ER -

Lewis acid catalyzed intramolecular [3+2] cross-cycloaddition of donor-acceptor cyclopropanes with carbonyls: A general strategy for the construction of acetal[n.2.1] skeletons

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