Knowledge graph based reasoning in medical image analysis: A scoping review

Automated computer-aided diagnosis (CAD) is becoming more significant in the field of medicine due to advancements in computer hardware performance and the progress of artificial intelligence. The knowledge graph is a structure for visually representing knowledge facts. In the last decade, a large body of work based on knowledge graphs has effectively improved the organization and interpretability of large-scale complex knowledge. Introducing knowledge graph inference into CAD is a research direction with significant potential. In this review, we briefly review the basic principles and application methods of knowledge graphs firstly. Then, we systematically organize and analyze the research and application of knowledge graphs in medical imaging-assisted diagnosis. We also summarize the shortcomings of the current research, such as medical data barriers and deficiencies, low utilization of multimodal information, and weak interpretability. Finally, we propose future research directions with possibilities and potentials to address the shortcomings of current approaches.