Joint analysis of gyral folding and fiber shape patterns

Xiang Yu, Hanbo Chen, Tuo Zhang, Xintao Hu, Lei Guo, Tianming Liu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

12 Scopus citations

Abstract

Cortical gyral folding pattern can be described by the hinge numbers, e.g., 2-hinge and 3-hinge gyri. Our recent studies have shown that joint analysis of 2-hinge gyral folding and its fiber connection patterns can be a powerful tool to elucidate the regularity and variability of gyral structures. However, other more complex gyral shape patterns such as 3-hinge gyri have not been investigated yet. In this paper, we proposed a novel computational framework to characterize 3-hinge gyral folding patterns and jointly analyze the correlation between folding and DTI-derived fiber orientation patterns in these regions. To characterize and differentiate these 3-hinge gyral folding patterns, an effective decision tree model is designed and applied to classify these 3-hinge gyral patches into the combinations of five basic sub-types of 'S', 'U', 'V', 'I', and other shapes. Then, the correlations between the shapes of these sub-types of 3-hinge gyri and their DTI-derived fiber connection patterns are quantitatively assessed, and our results demonstrated their close relationships. This work further replicated and strengthened our previous finding obtained in 2-hinge gyri that gyral folding patterns are closely correlated with fiber connection patterns.

Original languageEnglish
Title of host publicationISBI 2013 - 2013 IEEE 10th International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro
Pages85-88
Number of pages4
DOIs
StatePublished - 2013
Event2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013 - San Francisco, CA, United States
Duration: 7 Apr 201311 Apr 2013

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Conference

Conference2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013
Country/TerritoryUnited States
CitySan Francisco, CA
Period7/04/1311/04/13

Keywords

  • DTI
  • folding pattern
  • MRI
  • shape analysis

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