Investigation on osteoblast growth on the modified surface of porous titanium

Xu Guangsheng, Kou Hongchao, Li Ruolin, Liu Xianghong, Lu Tingli, Li Qi, Zhou Lian

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Three methods have been used to modify the porous titanium surface, which is the alkali heat treatment, alkali heat treatment + SBF solution soak and alkali heat treatment + precalcidied + SBF solution soak. The morphology of different surfaces was observed by scanning electron microscopy (SEM). The MC3T3-E1 osteoblast cell was cultured on the modified and unmodified surface of porous titanium with 3days and 7days, the morphology of osteoblast adhesion and growth on different surface was observed. The results showed that osteoblast adhere on the modified and unmodified surface of the porous titanium. Osteoblast on AHS and HA modified surface can grow and spread, but it cannot grow and spread on unmodified and AH modified surface of the porous titanium. Osteoblast can grow across the different titanium fibers of on HA modified surface of porous titanium. Osteoblast on the HA surface has the very good biological suitability, which is beneficial to the combination of bone tissue and porous titanium.

Original languageEnglish
Title of host publicationBiomaterial and Bioengineering
Pages98-103
Number of pages6
DOIs
StatePublished - 2013
Event2012 International Conference on Biomaterial and Bioengineering, ICBB 2012 - , Hong Kong
Duration: 19 Dec 201220 Dec 2012

Publication series

NameAdvanced Materials Research
Volume647
ISSN (Print)1022-6680

Conference

Conference2012 International Conference on Biomaterial and Bioengineering, ICBB 2012
Country/TerritoryHong Kong
Period19/12/1220/12/12

Keywords

  • In vitro
  • Osteoblast
  • Porous titanium
  • Suitability
  • Surface modification

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