Inertial Focusing Chip Based on Superposed Secondary Flows

Jianguo Feng; Qi Wang; Yuanming Ma; Honglong Chang; Gaobin Xu

doi:10.1109/NEMS51815.2021.9451414

Inertial Focusing Chip Based on Superposed Secondary Flows

Jianguo Feng, Qi Wang, Yuanming Ma, Honglong Chang, Gaobin Xu

Hefei University of Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Inertial focusing has been widely used in particle/cell separation and flow cytometry. In this work we presented an improved inertial focusing chip, consisting of an annular channel with obstacles distributed on the inner wall. Two types of secondary flows were generated and then superposed, thus enhanced the impact on particles. The simulation and experimental results showed that the enhanced secondary flow allowed precise focusing of particles and improved the focusing efficiency. The developed chip achieved a focusing width of ≈11.3 μm for 10.7 μm particles with a flow rate of ≈300 μL/min.

Original language	English
Title of host publication	Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	55-59
Number of pages	5
ISBN (Electronic)	9781665419413
DOIs	https://doi.org/10.1109/NEMS51815.2021.9451414
State	Published - 25 Apr 2021
Externally published	Yes
Event	16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021 - Xiamen, China Duration: 25 Apr 2021 → 29 Apr 2021

Publication series

Name	Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021

Conference

Conference	16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021
Country/Territory	China
City	Xiamen
Period	25/04/21 → 29/04/21

Access to Document

10.1109/NEMS51815.2021.9451414

Cite this

Feng, J., Wang, Q., Ma, Y., Chang, H., & Xu, G. (2021). Inertial Focusing Chip Based on Superposed Secondary Flows. In Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021 (pp. 55-59). Article 9451414 (Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NEMS51815.2021.9451414

Feng, Jianguo ; Wang, Qi ; Ma, Yuanming et al. / Inertial Focusing Chip Based on Superposed Secondary Flows. Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021. Institute of Electrical and Electronics Engineers Inc., 2021. pp. 55-59 (Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021).

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title = "Inertial Focusing Chip Based on Superposed Secondary Flows",

abstract = "Inertial focusing has been widely used in particle/cell separation and flow cytometry. In this work we presented an improved inertial focusing chip, consisting of an annular channel with obstacles distributed on the inner wall. Two types of secondary flows were generated and then superposed, thus enhanced the impact on particles. The simulation and experimental results showed that the enhanced secondary flow allowed precise focusing of particles and improved the focusing efficiency. The developed chip achieved a focusing width of ≈11.3 μm for 10.7 μm particles with a flow rate of ≈300 μL/min.",

author = "Jianguo Feng and Qi Wang and Yuanming Ma and Honglong Chang and Gaobin Xu",

note = "Publisher Copyright: {\textcopyright} 2021 IEEE.; 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021 ; Conference date: 25-04-2021 Through 29-04-2021",

year = "2021",

month = apr,

day = "25",

doi = "10.1109/NEMS51815.2021.9451414",

language = "英语",

series = "Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "55--59",

booktitle = "Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021",

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Feng, J, Wang, Q, Ma, Y, Chang, H & Xu, G 2021, Inertial Focusing Chip Based on Superposed Secondary Flows. in Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021., 9451414, Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021, Institute of Electrical and Electronics Engineers Inc., pp. 55-59, 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021, Xiamen, China, 25/04/21. https://doi.org/10.1109/NEMS51815.2021.9451414

Inertial Focusing Chip Based on Superposed Secondary Flows. / Feng, Jianguo; Wang, Qi; Ma, Yuanming et al.
Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021. Institute of Electrical and Electronics Engineers Inc., 2021. p. 55-59 9451414 (Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Inertial Focusing Chip Based on Superposed Secondary Flows

AU - Feng, Jianguo

AU - Wang, Qi

AU - Ma, Yuanming

AU - Chang, Honglong

AU - Xu, Gaobin

PY - 2021/4/25

Y1 - 2021/4/25

N2 - Inertial focusing has been widely used in particle/cell separation and flow cytometry. In this work we presented an improved inertial focusing chip, consisting of an annular channel with obstacles distributed on the inner wall. Two types of secondary flows were generated and then superposed, thus enhanced the impact on particles. The simulation and experimental results showed that the enhanced secondary flow allowed precise focusing of particles and improved the focusing efficiency. The developed chip achieved a focusing width of ≈11.3 μm for 10.7 μm particles with a flow rate of ≈300 μL/min.

AB - Inertial focusing has been widely used in particle/cell separation and flow cytometry. In this work we presented an improved inertial focusing chip, consisting of an annular channel with obstacles distributed on the inner wall. Two types of secondary flows were generated and then superposed, thus enhanced the impact on particles. The simulation and experimental results showed that the enhanced secondary flow allowed precise focusing of particles and improved the focusing efficiency. The developed chip achieved a focusing width of ≈11.3 μm for 10.7 μm particles with a flow rate of ≈300 μL/min.

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U2 - 10.1109/NEMS51815.2021.9451414

DO - 10.1109/NEMS51815.2021.9451414

M3 - 会议稿件

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T3 - Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021

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EP - 59

BT - Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021

Y2 - 25 April 2021 through 29 April 2021

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Feng J, Wang Q, Ma Y, Chang H, Xu G. Inertial Focusing Chip Based on Superposed Secondary Flows. In Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021. Institute of Electrical and Electronics Engineers Inc. 2021. p. 55-59. 9451414. (Proceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021). doi: 10.1109/NEMS51815.2021.9451414

Inertial Focusing Chip Based on Superposed Secondary Flows

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