Inertial Focusing Chip Based on Superposed Secondary Flows

Jianguo Feng, Qi Wang, Yuanming Ma, Honglong Chang, Gaobin Xu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Inertial focusing has been widely used in particle/cell separation and flow cytometry. In this work we presented an improved inertial focusing chip, consisting of an annular channel with obstacles distributed on the inner wall. Two types of secondary flows were generated and then superposed, thus enhanced the impact on particles. The simulation and experimental results showed that the enhanced secondary flow allowed precise focusing of particles and improved the focusing efficiency. The developed chip achieved a focusing width of ≈11.3 μm for 10.7 μm particles with a flow rate of ≈300 μL/min.

Original languageEnglish
Title of host publicationProceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages55-59
Number of pages5
ISBN (Electronic)9781665419413
DOIs
StatePublished - 25 Apr 2021
Externally publishedYes
Event16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021 - Xiamen, China
Duration: 25 Apr 202129 Apr 2021

Publication series

NameProceedings of the 16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021

Conference

Conference16th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2021
Country/TerritoryChina
CityXiamen
Period25/04/2129/04/21

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