Fabrication of micron-sized BSA-imprinted polymers with outstanding adsorption capacity based on poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres

Yufei Wang, Jingjing Zhou, Chen Wu, Lei Tian, Baoliang Zhang, Qiuyu Zhang

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Monodisperse poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres have been fabricated by seed polymerization. From the SEM images, it is known that the obtained PGMA/PS microspheres have three different morphologies: raspberry-shaped, golf-shaped and porous structures. Based on the successful fabrication of these micropheres, bovine serum albumin (BSA)-imprinted PGMA/PS microspheres were fabricated via dopamine auto-polymerization in alkaline solution. Because dopamine does not affect the validity of the protein structure, the imprinted cavity structure on the surface of the MIPs can match the template protein molecules completely. The obtained micron-sized BSA-imprinted PGMA/PS microspheres have an excellent saturation adsorption capacity (Q = 72.7 mg g-1) and good selective adsorption for BSA (IF = 4.6).

Original languageEnglish
Pages (from-to)5860-5866
Number of pages7
JournalJournal of Materials Chemistry B
Volume6
Issue number37
DOIs
StatePublished - 2018

Fingerprint

Dive into the research topics of 'Fabrication of micron-sized BSA-imprinted polymers with outstanding adsorption capacity based on poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres'. Together they form a unique fingerprint.

Cite this