Effects of physical environments on nucleation of protein crystals: a review

Ruiqing Chen, Jun Liu, Qinqin Lu, Yongming Liu, Dachuan Yin

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

This paper reviews the effects of physical environments (including light, electric field, ultrasound, magnetic field, microgravity, temperature, mechanical vibration, and heterogeneous nucleation interface) on protein crystal nucleation. The research results are summarized and the possible mechanisms of the effects are discussed. In the end of this review, the application prospects of these physical environments (including coupled environments) in protein crystallization are presented.

Original languageEnglish
Pages (from-to)9-17
Number of pages9
JournalShengwu Gongcheng Xuebao/Chinese Journal of Biotechnology
Volume27
Issue number1
StatePublished - Jan 2011

Keywords

  • Crystal
  • Nucleation
  • Physical environment
  • Protein

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