DEP-on-a-chip: Dielectrophoresis applied to microfluidic platforms

Haoqing Zhang, Honglong Chang, Pavel Neuzil

Research output: Contribution to journalReview articlepeer-review

140 Scopus citations

Abstract

Dielectric particles in a non-uniform electric field are subject to a force caused by a phenomenon called dielectrophoresis (DEP). DEP is a commonly used technique in microfluidics for particle or cell separation. In comparison with other separation methods, DEP has the unique advantage of being label-free, fast, and accurate. It has been widely applied in microfluidics for bio-molecular diagnostics and medical and polymer research. This review introduces the basic theory of DEP, its advantages compared with other separation methods, and its applications in recent years, in particular, focusing on the different electrode types integrated into microfluidic chips, fabrication techniques, and operation principles.

Original languageEnglish
Article number423
JournalMicromachines
Volume10
Issue number6
DOIs
StatePublished - 1 Jun 2019

Keywords

  • Castellated electrodes
  • Dielectrophoresis
  • Interdigitated electrode
  • Microfluidics
  • Parallel electrodes
  • Three-dimensional electrodes
  • Two-dimensional electrodes

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