TY - JOUR
T1 - Demystifying the coordination polymers triggered fluorescence immunoassay
T2 - State of the art and future perspectives
AU - Zhang, Qunzheng
AU - Lu, Chengyi
AU - Wang, Ruifei
AU - Han, Weiwei
AU - Ke, Congye
AU - Wang, Sichang
AU - Zhang, Xunli
AU - Wang, Jianlong
N1 - Publisher Copyright:
© 2023 Elsevier B.V.
PY - 2023/8/1
Y1 - 2023/8/1
N2 - Fluorescence immunoassay has shown attractive potential for advancing public health due to its merits of integrating the superior specificity of immunological recognition and brilliant sensitivity of fluorescence sensors. Over the past decades, coordination polymers (CPs) have been actively pursued in the construction of fluorescence immunoassays because of their propensity for surface engineering, high compositional diversity and structural flexibility. These virtues endow CPs with immense feasibility in the target-oriented manufacturing of sensing platforms for specific applications. Despite the fact that numerous reviews on luminescent CPs or immunoassays from various perspectives have been published, a comprehensive review of CPs-based fluorescence immunoassay with sensing subjects is still lacking, and it must be organized in an all-inclusive manner with an in-depth discussion of the detection mechanisms. To better facilitate the development of this field, the fluorescence mechanism of CPs, general fluorescence sensing mechanism, and mechanism of CPs-driven fluorescence immunoassay was demystified before systematically highlighting the current state of the art in this field. Accordingly, recent applications were discussed after being classified into four categories based on the function of CPs, including direct use-, disintegration-, reaction-, and mediated-type. The objective of this review is to provide readers with an extensive overview, prospective challenges, and future perspectives for rational design of CPs-based fluorescence immunoassays.
AB - Fluorescence immunoassay has shown attractive potential for advancing public health due to its merits of integrating the superior specificity of immunological recognition and brilliant sensitivity of fluorescence sensors. Over the past decades, coordination polymers (CPs) have been actively pursued in the construction of fluorescence immunoassays because of their propensity for surface engineering, high compositional diversity and structural flexibility. These virtues endow CPs with immense feasibility in the target-oriented manufacturing of sensing platforms for specific applications. Despite the fact that numerous reviews on luminescent CPs or immunoassays from various perspectives have been published, a comprehensive review of CPs-based fluorescence immunoassay with sensing subjects is still lacking, and it must be organized in an all-inclusive manner with an in-depth discussion of the detection mechanisms. To better facilitate the development of this field, the fluorescence mechanism of CPs, general fluorescence sensing mechanism, and mechanism of CPs-driven fluorescence immunoassay was demystified before systematically highlighting the current state of the art in this field. Accordingly, recent applications were discussed after being classified into four categories based on the function of CPs, including direct use-, disintegration-, reaction-, and mediated-type. The objective of this review is to provide readers with an extensive overview, prospective challenges, and future perspectives for rational design of CPs-based fluorescence immunoassays.
KW - Coordination chemistry
KW - Coordination polymers
KW - Fluorescence
KW - Immunoassay
KW - Mechanism
UR - http://www.scopus.com/inward/record.url?scp=85154530243&partnerID=8YFLogxK
U2 - 10.1016/j.ccr.2023.215188
DO - 10.1016/j.ccr.2023.215188
M3 - 文献综述
AN - SCOPUS:85154530243
SN - 0010-8545
VL - 488
JO - Coordination Chemistry Reviews
JF - Coordination Chemistry Reviews
M1 - 215188
ER -