Antifouling molecularly imprinted membranes for pretreatment of milk samples: Selective separation and detection of lincomycin

Zeqing Dong, Jian Lu, Yilin Wu, Minjia Meng, Chao Yu, Chang Sun, Muning Chen, Zulin Da, Yongsheng Yan

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

As a veterinary antibiotic, lincomycin (LIN) residues in milk are raising concerns of public on account of potential harm to human health. Efficient strategy is eagerly desired for detection of LIN from milk samples. Hence, lincomycin molecularly imprinted membranes (LINMIMs) were developed for selective separation of LIN as an efficient pretreatment of milk samples. The synergistic effect of polyethylenimine and dopamine provided effective antifouling performance by improving the hydrophilicity. Based on click chemistry, specific recognition sites were facilely formed on membranes using 4-vinylpyridine as functional monomers. The satisfactory rebinding capacity (151.62 mg g−1), permselectivity (4.43), together with the linear dependence (R2 = 0.9902) of concentrations in eluents and original samples. Moreover, the method was utilized to determine LIN from milk, with good recovery and relative standard deviation. Achievements in this work will actively promote the development of efficient detection technology.

Original languageEnglish
Article number127477
JournalFood Chemistry
Volume333
DOIs
StatePublished - 15 Dec 2020
Externally publishedYes

Keywords

  • Antifouling
  • Lincomycin
  • Milk
  • Molecularly imprinted membrane
  • Selective detection

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