Abstract
An unprecedented method for the synthesis of highly functionalized indanes from arynes and α,γ-diketo esters is described. Importantly, mild and nearly pH-neutral conditions ensure excellent functional group tolerance. Theoretical studies indicated that the reaction proceeds through a benzocyclobutane intermediate.
Original language | English |
---|---|
Pages (from-to) | 941-945 |
Number of pages | 5 |
Journal | Organic Letters |
Volume | 21 |
Issue number | 4 |
DOIs | |
State | Published - 15 Feb 2019 |
Externally published | Yes |