Synthesis, crystal structures and in vitro antitumor activities of some organoantimony arylhydroxamates

Guo Cang Wang; Yong Na Lu; Jian Xiao; Lin Yu; Hai Bin Song; Jin Shan Li; Jing Rong Cui; Rui Qing Wang; Fu Xiang Ran

doi:10.1016/j.jorganchem.2004.09.002

Synthesis, crystal structures and in vitro antitumor activities of some organoantimony arylhydroxamates

Guo Cang Wang
, Yong Na Lu
, Jian Xiao
, Lin Yu
, Hai Bin Song
, Jin Shan Li
, Jing Rong Cui
, Rui Qing Wang
, Fu Xiang Ran

Nankai University
Peking University

科研成果: 期刊稿件 › 文章 › 同行评审

44 引用（Scopus）

摘要

A series of novel organoantimony arylhydroxamates with the formulae [Ar ₃SbL ₂] ^-[HNEt ₃] ⁺ (LH = arylhydroxamic acid; Ar = C ₆H ₅, 4-CH ₃C ₆H ₄, 3-CH ₃C ₆H ₄, 4-ClC ₆H ₄, 4-FC ₆H ₄) and (4-CH ₃C ₆H ₄) ₄SbL were synthesized and characterized by elemental analysis, IR, ¹H NMR and mass spectroscopy. The crystal structures of (4-CH ₃C ₆H ₄) ₄SbL and [Ph ₃SbL ₂] ^-[HNEt ₃] ⁺ were determined by X-ray diffraction. The in vitro antitumor activities of all compounds against three human cancer cells are reported.

源语言	英语
页（从-至）	151-156
页数	6
期刊	Journal of Organometallic Chemistry
卷	690
期	1
DOI	https://doi.org/10.1016/j.jorganchem.2004.09.002
出版状态	已出版 - 3 1月 2005
已对外发布	是

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

访问文件

10.1016/j.jorganchem.2004.09.002

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{77ee5b9e4d4d44e9b97956b958862217,

title = "Synthesis, crystal structures and in vitro antitumor activities of some organoantimony arylhydroxamates",

abstract = "A series of novel organoantimony arylhydroxamates with the formulae [Ar 3SbL 2] -[HNEt 3] + (LH = arylhydroxamic acid; Ar = C 6H 5, 4-CH 3C 6H 4, 3-CH 3C 6H 4, 4-ClC 6H 4, 4-FC 6H 4) and (4-CH 3C 6H 4) 4SbL were synthesized and characterized by elemental analysis, IR, 1H NMR and mass spectroscopy. The crystal structures of (4-CH 3C 6H 4) 4SbL and [Ph 3SbL 2] -[HNEt 3] + were determined by X-ray diffraction. The in vitro antitumor activities of all compounds against three human cancer cells are reported.",

keywords = "Antitumor activity, Arylhydroxamic acid, Crystal structures, Organoantimony",

author = "Wang, \{Guo Cang\} and Lu, \{Yong Na\} and Jian Xiao and Lin Yu and Song, \{Hai Bin\} and Li, \{Jin Shan\} and Cui, \{Jing Rong\} and Wang, \{Rui Qing\} and Ran, \{Fu Xiang\}",

year = "2005",

month = jan,

day = "3",

doi = "10.1016/j.jorganchem.2004.09.002",

language = "英语",

volume = "690",

pages = "151--156",

journal = "Journal of Organometallic Chemistry",

issn = "0022-328X",

publisher = "Elsevier B.V.",

number = "1",

}

TY - JOUR

T1 - Synthesis, crystal structures and in vitro antitumor activities of some organoantimony arylhydroxamates

AU - Wang, Guo Cang

AU - Lu, Yong Na

AU - Xiao, Jian

AU - Yu, Lin

AU - Song, Hai Bin

AU - Li, Jin Shan

AU - Cui, Jing Rong

AU - Wang, Rui Qing

AU - Ran, Fu Xiang

PY - 2005/1/3

Y1 - 2005/1/3

N2 - A series of novel organoantimony arylhydroxamates with the formulae [Ar 3SbL 2] -[HNEt 3] + (LH = arylhydroxamic acid; Ar = C 6H 5, 4-CH 3C 6H 4, 3-CH 3C 6H 4, 4-ClC 6H 4, 4-FC 6H 4) and (4-CH 3C 6H 4) 4SbL were synthesized and characterized by elemental analysis, IR, 1H NMR and mass spectroscopy. The crystal structures of (4-CH 3C 6H 4) 4SbL and [Ph 3SbL 2] -[HNEt 3] + were determined by X-ray diffraction. The in vitro antitumor activities of all compounds against three human cancer cells are reported.

AB - A series of novel organoantimony arylhydroxamates with the formulae [Ar 3SbL 2] -[HNEt 3] + (LH = arylhydroxamic acid; Ar = C 6H 5, 4-CH 3C 6H 4, 3-CH 3C 6H 4, 4-ClC 6H 4, 4-FC 6H 4) and (4-CH 3C 6H 4) 4SbL were synthesized and characterized by elemental analysis, IR, 1H NMR and mass spectroscopy. The crystal structures of (4-CH 3C 6H 4) 4SbL and [Ph 3SbL 2] -[HNEt 3] + were determined by X-ray diffraction. The in vitro antitumor activities of all compounds against three human cancer cells are reported.

KW - Antitumor activity

KW - Arylhydroxamic acid

KW - Crystal structures

KW - Organoantimony

UR - https://www.scopus.com/pages/publications/11144323888

U2 - 10.1016/j.jorganchem.2004.09.002

DO - 10.1016/j.jorganchem.2004.09.002

M3 - 文章

AN - SCOPUS:11144323888

SN - 0022-328X

VL - 690

SP - 151

EP - 156

JO - Journal of Organometallic Chemistry

JF - Journal of Organometallic Chemistry

IS - 1

ER -

Synthesis, crystal structures and in vitro antitumor activities of some organoantimony arylhydroxamates

摘要

联合国可持续发展目标

访问文件

其它文件与链接

学术指纹

引用此