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Polymeric microneedles' swelling property characterizations using micro-optical coherence tomography

  • Xiaojun Yu
  • , Razina Z. Seeni
  • , Linbo Liu
  • , Chenjie Xu
  • Nanyang Technological University

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

We report on noninvasive characterization of MNs' real-time swelling property in mice-skin using a lab-built micro-optical coherence tomography (µOCT). Specifically, we propose to encapsulate the iron-oxide (Fe3O4) nanoparticles into polymeric MNs as contrast agent to enhance OCT image contrast, and then evaluate its influences on contrast enhancement quantitatively. The MNs' real-time temporal swelling behaviors in mice-skin are recorded and analyzed. This is the first quantitative study on MNs' temporal swelling property in biological tissue using µOCT.

源语言英语
主期刊名Conference on Lasers and Electro-Optics/Pacific Rim, CLEOPR 2017
出版商Optica Publishing Group (formerly OSA)
ISBN(印刷版)9781509062904
出版状态已出版 - 2017
活动Conference on Lasers and Electro-Optics/Pacific Rim, CLEOPR 2017 - Singapore, 新加坡
期限: 31 7月 20174 8月 2017

出版系列

姓名Optics InfoBase Conference Papers
Part F122-CLEOPR 2017
ISSN(电子版)2162-2701

会议

会议Conference on Lasers and Electro-Optics/Pacific Rim, CLEOPR 2017
国家/地区新加坡
Singapore
时期31/07/174/08/17

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