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PneumoLLM: Harnessing the power of large language model for pneumoconiosis diagnosis

  • Meiyue Song
  • , Jiarui Wang
  • , Zhihua Yu
  • , Jiaxin Wang
  • , Le Yang
  • , Yuting Lu
  • , Baicun Li
  • , Xue Wang
  • , Xiaoxu Wang
  • , Qinghua Huang
  • , Zhijun Li
  • , Nikolaos I. Kanellakis
  • , Jiangfeng Liu
  • , Jing Wang
  • , Binglu Wang
  • , Juntao Yang
  • Chinese Academy of Medical Sciences
  • State Key Laboratory of Respiratory Health and Multimorbidity
  • Northwestern Polytechnical University Xian
  • Jinneng Holding Coal Industry Group Co. Ltd Occupational Disease Precaution Clinic
  • Tsinghua University
  • Chang'an University
  • China-Japan Friendship Hospital
  • the Second Affiliated Hospital of Harbin Medical University
  • Harbin Medical University
  • Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
  • Tongji University
  • University of Oxford
  • Oxford University Hospitals NHS Foundation Trust
  • State Key Laboratory of Common Mechanism Research for Major Diseases

科研成果: 期刊稿件文章同行评审

32 引用 (Scopus)

摘要

The conventional pretraining-and-finetuning paradigm, while effective for common diseases with ample data, faces challenges in diagnosing data-scarce occupational diseases like pneumoconiosis. Recently, large language models (LLMs) have exhibits unprecedented ability when conducting multiple tasks in dialogue, bringing opportunities to diagnosis. A common strategy might involve using adapter layers for vision–language alignment and diagnosis in a dialogic manner. Yet, this approach often requires optimization of extensive learnable parameters in the text branch and the dialogue head, potentially diminishing the LLMs’ efficacy, especially with limited training data. In our work, we innovate by eliminating the text branch and substituting the dialogue head with a classification head. This approach presents a more effective method for harnessing LLMs in diagnosis with fewer learnable parameters. Furthermore, to balance the retention of detailed image information with progression towards accurate diagnosis, we introduce the contextual multi-token engine. This engine is specialized in adaptively generating diagnostic tokens. Additionally, we propose the information emitter module, which unidirectionally emits information from image tokens to diagnosis tokens. Comprehensive experiments validate the superiority of our methods.

源语言英语
期刊论文编号103248
期刊Medical Image Analysis
97
DOI
出版状态已出版 - 10月 2024

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