Photothermal-triggered release of singlet oxygen from an endoperoxide-containing polymeric carrier for killing cancer cells

Wen Lv; Huiting Xia; Kenneth Yin Zhang; Zejing Chen; Shujuan Liu; Wei Huang; Qiang Zhao

doi:10.1039/c7mh00726d

Photothermal-triggered release of singlet oxygen from an endoperoxide-containing polymeric carrier for killing cancer cells

Wen Lv
, Huiting Xia
, Kenneth Yin Zhang
, Zejing Chen
, Shujuan Liu
, Wei Huang
, Qiang Zhao

柔性电子研究院

Nanjing University of Posts and Telecommunications

科研成果: 期刊稿件 › 文章 › 同行评审

62 引用（Scopus）

摘要

A polymeric carrier containing a naphthalene and iridium(iii) complex was developed to deliver extracellular singlet oxygen (¹O₂) into cancer cells to induce oxidative damage without intracellular O₂ consumption. The release of ¹O₂ was triggered by the photothermal effect of Au nanorods upon irradiation at 808 nm, realizing controllable therapy combining both oxidative and photothermal damage.

源语言	英语
页（从-至）	1185-1189
页数	5
期刊	Materials Horizons
卷	4
期	6
DOI	https://doi.org/10.1039/c7mh00726d
出版状态	已出版 - 11月 2017

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

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10.1039/c7mh00726d

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引用此

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title = "Photothermal-triggered release of singlet oxygen from an endoperoxide-containing polymeric carrier for killing cancer cells",

abstract = "A polymeric carrier containing a naphthalene and iridium(iii) complex was developed to deliver extracellular singlet oxygen (1O2) into cancer cells to induce oxidative damage without intracellular O2 consumption. The release of 1O2 was triggered by the photothermal effect of Au nanorods upon irradiation at 808 nm, realizing controllable therapy combining both oxidative and photothermal damage.",

author = "Wen Lv and Huiting Xia and Zhang, \{Kenneth Yin\} and Zejing Chen and Shujuan Liu and Wei Huang and Qiang Zhao",

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doi = "10.1039/c7mh00726d",

language = "英语",

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AU - Lv, Wen

AU - Xia, Huiting

AU - Zhang, Kenneth Yin

AU - Chen, Zejing

AU - Liu, Shujuan

AU - Huang, Wei

AU - Zhao, Qiang

PY - 2017/11

Y1 - 2017/11

N2 - A polymeric carrier containing a naphthalene and iridium(iii) complex was developed to deliver extracellular singlet oxygen (1O2) into cancer cells to induce oxidative damage without intracellular O2 consumption. The release of 1O2 was triggered by the photothermal effect of Au nanorods upon irradiation at 808 nm, realizing controllable therapy combining both oxidative and photothermal damage.

AB - A polymeric carrier containing a naphthalene and iridium(iii) complex was developed to deliver extracellular singlet oxygen (1O2) into cancer cells to induce oxidative damage without intracellular O2 consumption. The release of 1O2 was triggered by the photothermal effect of Au nanorods upon irradiation at 808 nm, realizing controllable therapy combining both oxidative and photothermal damage.

UR - https://www.scopus.com/pages/publications/85032742994

U2 - 10.1039/c7mh00726d

DO - 10.1039/c7mh00726d

M3 - 文章

AN - SCOPUS:85032742994

SN - 2051-6347

VL - 4

SP - 1185

EP - 1189

JO - Materials Horizons

JF - Materials Horizons

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ER -

Photothermal-triggered release of singlet oxygen from an endoperoxide-containing polymeric carrier for killing cancer cells

摘要

联合国可持续发展目标

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