On-chip enantioselective refractive-index sensing enabled by chiral metal-organic frameworks

Peng Qin; Ruyuan Zhou; Xinghang Ma; Xuetao Gan

doi:10.1364/PRJ.583977

On-chip enantioselective refractive-index sensing enabled by chiral metal-organic frameworks

Peng Qin
, Ruyuan Zhou
, Xinghang Ma
, Xuetao Gan

微电子学院

Northwestern Polytechnical University Xian

科研成果: 期刊稿件 › 文章 › 同行评审

摘要

High-sensitivity identification and quantification of chiral molecules are vital in life sciences and pharmaceutical analysis. We demonstrate an on-chip chiral sensing platform based on microring resonator arrays functionalized with chiral Cu₂(DCam)₂(dabco) metal-organic frameworks (MOFs)· The layer-by-layer-assembled MOF films enable enantioselective adsorption of R - and S -limonene through synergistic chiral pore and Cu-site interactions.

源语言	英语
页（从-至）	2298-2305
页数	8
期刊	Photonics Research
卷	14
期	5
DOI	https://doi.org/10.1364/PRJ.583977
出版状态	已出版 - 5月 2026

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abstract = "High-sensitivity identification and quantification of chiral molecules are vital in life sciences and pharmaceutical analysis. We demonstrate an on-chip chiral sensing platform based on microring resonator arrays functionalized with chiral Cu2(DCam)2(dabco) metal-organic frameworks (MOFs)· The layer-by-layer-assembled MOF films enable enantioselective adsorption of R - and S -limonene through synergistic chiral pore and Cu-site interactions.",

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AU - Ma, Xinghang

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Y1 - 2026/5

N2 - High-sensitivity identification and quantification of chiral molecules are vital in life sciences and pharmaceutical analysis. We demonstrate an on-chip chiral sensing platform based on microring resonator arrays functionalized with chiral Cu2(DCam)2(dabco) metal-organic frameworks (MOFs)· The layer-by-layer-assembled MOF films enable enantioselective adsorption of R - and S -limonene through synergistic chiral pore and Cu-site interactions.

AB - High-sensitivity identification and quantification of chiral molecules are vital in life sciences and pharmaceutical analysis. We demonstrate an on-chip chiral sensing platform based on microring resonator arrays functionalized with chiral Cu2(DCam)2(dabco) metal-organic frameworks (MOFs)· The layer-by-layer-assembled MOF films enable enantioselective adsorption of R - and S -limonene through synergistic chiral pore and Cu-site interactions.

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On-chip enantioselective refractive-index sensing enabled by chiral metal-organic frameworks

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