摘要
MicroRNAs (miRNAs) play critical roles in the development and progression of various diseases. However, traditional experimental approaches are difficult to detect potential human miRNA-disease associations from the vast amount of biological data. Therefore, computational techniques could be of significant value. In this work, we proposed a miRNA sequence similarity calculation model (MISSIM) to large-scale predict miRNA-disease associations by combined Chaos Game Representation (CGR) with Broad Learning System (BLS). In the five-cross-validation experiment, MISSIM achieved ACC of 0.8424 on the HMDD.
| 源语言 | 英语 |
|---|---|
| 主期刊名 | Intelligent Computing - 15th International Conference, ICIC 2019, Proceeding |
| 编辑 | De-Shuang Huang, Zhi-Kai Huang, Abir Hussain |
| 出版商 | Springer Verlag |
| 页 | 392-398 |
| 页数 | 7 |
| ISBN(印刷版) | 9783030267650 |
| DOI | |
| 出版状态 | 已出版 - 2019 |
| 已对外发布 | 是 |
| 活动 | 15th International Conference on Intelligent Computing, ICIC 2019 - Nanchang, 中国 期限: 3 8月 2019 → 6 8月 2019 |
出版系列
| 姓名 | Lecture Notes in Computer Science |
|---|---|
| 卷 | 11645 LNAI |
| ISSN(印刷版) | 0302-9743 |
| ISSN(电子版) | 1611-3349 |
会议
| 会议 | 15th International Conference on Intelligent Computing, ICIC 2019 |
|---|---|
| 国家/地区 | 中国 |
| 市 | Nanchang |
| 时期 | 3/08/19 → 6/08/19 |
联合国可持续发展目标
此成果有助于实现下列可持续发展目标:
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可持续发展目标 3 良好健康与福祉
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