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MISSIM: Improved miRNA-Disease Association Prediction Model Based on Chaos Game Representation and Broad Learning System

  • Kai Zheng
  • , Zhu Hong You
  • , Lei Wang
  • , Yi Ran Li
  • , Yan Bin Wang
  • , Han Jing Jiang
  • China University of Mining and Technology
  • Xinjiang Technical Institute of Physics and Chemistry

科研成果: 书/报告/会议事项章节会议稿件同行评审

15 引用 (Scopus)

摘要

MicroRNAs (miRNAs) play critical roles in the development and progression of various diseases. However, traditional experimental approaches are difficult to detect potential human miRNA-disease associations from the vast amount of biological data. Therefore, computational techniques could be of significant value. In this work, we proposed a miRNA sequence similarity calculation model (MISSIM) to large-scale predict miRNA-disease associations by combined Chaos Game Representation (CGR) with Broad Learning System (BLS). In the five-cross-validation experiment, MISSIM achieved ACC of 0.8424 on the HMDD.

源语言英语
主期刊名Intelligent Computing - 15th International Conference, ICIC 2019, Proceeding
编辑De-Shuang Huang, Zhi-Kai Huang, Abir Hussain
出版商Springer Verlag
392-398
页数7
ISBN(印刷版)9783030267650
DOI
出版状态已出版 - 2019
已对外发布
活动15th International Conference on Intelligent Computing, ICIC 2019 - Nanchang, 中国
期限: 3 8月 20196 8月 2019

出版系列

姓名Lecture Notes in Computer Science
11645 LNAI
ISSN(印刷版)0302-9743
ISSN(电子版)1611-3349

会议

会议15th International Conference on Intelligent Computing, ICIC 2019
国家/地区中国
Nanchang
时期3/08/196/08/19

联合国可持续发展目标

此成果有助于实现下列可持续发展目标:

  1. 可持续发展目标 3 - 良好健康与福祉
    可持续发展目标 3 良好健康与福祉

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