Microfluidic device based on deep reactive ion etching process and its lag effect for single cell capture and extraction

Jianguo Feng; Zdenka Fohlerová; Xiaocheng Liu; Honglong Chang; Pavel Neužil

doi:10.1016/j.snb.2018.04.179

Microfluidic device based on deep reactive ion etching process and its lag effect for single cell capture and extraction

Jianguo Feng
, Zdenka Fohlerová
, Xiaocheng Liu
, Honglong Chang
, Pavel Neužil

机电学院

科研成果: 期刊稿件 › 文章 › 同行评审

15 引用（Scopus）

摘要

We introduced a microfluidic device for high-efficiency single cell capture and their subsequent extraction. It was fabricated by using a deep reactive ion etching process taking advantage of the lag effect. We accomplished single cell capture based on the least flow resistance path principle as well as independent extraction of individual captured cells to perform their subsequent analysis. The device was performed with >99% single cell capture efficiency.

源语言	英语
页（从-至）	288-292
页数	5
期刊	Sensors and Actuators, B: Chemical
卷	269
DOI	https://doi.org/10.1016/j.snb.2018.04.179
出版状态	已出版 - 15 9月 2018

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abstract = "We introduced a microfluidic device for high-efficiency single cell capture and their subsequent extraction. It was fabricated by using a deep reactive ion etching process taking advantage of the lag effect. We accomplished single cell capture based on the least flow resistance path principle as well as independent extraction of individual captured cells to perform their subsequent analysis. The device was performed with >99\% single cell capture efficiency.",

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AU - Feng, Jianguo

AU - Fohlerová, Zdenka

AU - Liu, Xiaocheng

AU - Chang, Honglong

AU - Neužil, Pavel

PY - 2018/9/15

Y1 - 2018/9/15

N2 - We introduced a microfluidic device for high-efficiency single cell capture and their subsequent extraction. It was fabricated by using a deep reactive ion etching process taking advantage of the lag effect. We accomplished single cell capture based on the least flow resistance path principle as well as independent extraction of individual captured cells to perform their subsequent analysis. The device was performed with >99% single cell capture efficiency.

AB - We introduced a microfluidic device for high-efficiency single cell capture and their subsequent extraction. It was fabricated by using a deep reactive ion etching process taking advantage of the lag effect. We accomplished single cell capture based on the least flow resistance path principle as well as independent extraction of individual captured cells to perform their subsequent analysis. The device was performed with >99% single cell capture efficiency.

KW - Deep reactive ion etching

KW - Lag effect

KW - Microfluidic device

KW - Single cell capture and extraction

KW - The least flow resistance path

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DO - 10.1016/j.snb.2018.04.179

M3 - 文章

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JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

ER -

Microfluidic device based on deep reactive ion etching process and its lag effect for single cell capture and extraction

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