J-Aggregate squaraine nanoparticles with bright NIR-II fluorescence for imaging guided photothermal therapy

Pengfei Sun; Qi Wu; Xiaoli Sun; Han Miao; Weixing Deng; Wansu Zhang; Quli Fan; Wei Huang

doi:10.1039/c8cc08096h

J-Aggregate squaraine nanoparticles with bright NIR-II fluorescence for imaging guided photothermal therapy

Pengfei Sun
, Qi Wu
, Xiaoli Sun
, Han Miao
, Weixing Deng
, Wansu Zhang
, Quli Fan
, Wei Huang

柔性电子研究院

Nanjing University of Posts and Telecommunications
Georgia Institute of Technology

科研成果: 期刊稿件 › 文章 › 同行评审

161 引用（Scopus）

摘要

We introduce a novel strategy to enhance the fluorescence brightness of organic-molecule-based nanoparticles in the second near-infrared window (NIR-II, 1000-1700 nm) by fabricating J-aggregate nanoparticles SQP-NPs_(J). Our prepared J-aggregate nanoparticles SQP-NPs_(J) show an emission maximum near 1100 nm, and the emission intensity is 4.8-fold higher than that of H-aggregate SQP-NPs_(H). In addition, SQP-NPs_(J) can be used for NIR-II imaging guided photothermal therapy on MCF-7 tumor-bearing mice due to the fact that SQP-NPs_(J) have highly effective photothermal properties, which are significant for precise tumor diagnostics and treatments.

源语言	英语
页（从-至）	13395-13398
页数	4
期刊	Chemical Communications
卷	54
期	95
DOI	https://doi.org/10.1039/c8cc08096h
出版状态	已出版 - 2018

访问文件

10.1039/c8cc08096h

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{5cdd5a9c7d854b20a314d613ef61b3c8,

title = "J-Aggregate squaraine nanoparticles with bright NIR-II fluorescence for imaging guided photothermal therapy",

abstract = "We introduce a novel strategy to enhance the fluorescence brightness of organic-molecule-based nanoparticles in the second near-infrared window (NIR-II, 1000-1700 nm) by fabricating J-aggregate nanoparticles SQP-NPs(J). Our prepared J-aggregate nanoparticles SQP-NPs(J) show an emission maximum near 1100 nm, and the emission intensity is 4.8-fold higher than that of H-aggregate SQP-NPs(H). In addition, SQP-NPs(J) can be used for NIR-II imaging guided photothermal therapy on MCF-7 tumor-bearing mice due to the fact that SQP-NPs(J) have highly effective photothermal properties, which are significant for precise tumor diagnostics and treatments.",

author = "Pengfei Sun and Qi Wu and Xiaoli Sun and Han Miao and Weixing Deng and Wansu Zhang and Quli Fan and Wei Huang",

note = "Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c8cc08096h",

language = "英语",

volume = "54",

pages = "13395--13398",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "95",

}

TY - JOUR

T1 - J-Aggregate squaraine nanoparticles with bright NIR-II fluorescence for imaging guided photothermal therapy

AU - Sun, Pengfei

AU - Wu, Qi

AU - Sun, Xiaoli

AU - Miao, Han

AU - Deng, Weixing

AU - Zhang, Wansu

AU - Fan, Quli

AU - Huang, Wei

PY - 2018

Y1 - 2018

N2 - We introduce a novel strategy to enhance the fluorescence brightness of organic-molecule-based nanoparticles in the second near-infrared window (NIR-II, 1000-1700 nm) by fabricating J-aggregate nanoparticles SQP-NPs(J). Our prepared J-aggregate nanoparticles SQP-NPs(J) show an emission maximum near 1100 nm, and the emission intensity is 4.8-fold higher than that of H-aggregate SQP-NPs(H). In addition, SQP-NPs(J) can be used for NIR-II imaging guided photothermal therapy on MCF-7 tumor-bearing mice due to the fact that SQP-NPs(J) have highly effective photothermal properties, which are significant for precise tumor diagnostics and treatments.

AB - We introduce a novel strategy to enhance the fluorescence brightness of organic-molecule-based nanoparticles in the second near-infrared window (NIR-II, 1000-1700 nm) by fabricating J-aggregate nanoparticles SQP-NPs(J). Our prepared J-aggregate nanoparticles SQP-NPs(J) show an emission maximum near 1100 nm, and the emission intensity is 4.8-fold higher than that of H-aggregate SQP-NPs(H). In addition, SQP-NPs(J) can be used for NIR-II imaging guided photothermal therapy on MCF-7 tumor-bearing mice due to the fact that SQP-NPs(J) have highly effective photothermal properties, which are significant for precise tumor diagnostics and treatments.

UR - https://www.scopus.com/pages/publications/85057196881

U2 - 10.1039/c8cc08096h

DO - 10.1039/c8cc08096h

M3 - 文章

C2 - 30426114

AN - SCOPUS:85057196881

SN - 1359-7345

VL - 54

SP - 13395

EP - 13398

JO - Chemical Communications

JF - Chemical Communications

IS - 95

ER -

J-Aggregate squaraine nanoparticles with bright NIR-II fluorescence for imaging guided photothermal therapy

摘要

访问文件

其它文件与链接

指纹

引用此