In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging

Li Shang; Linxiao Yang; Haixia Wang; Gerd Ulrich Nienhaus

doi:10.1002/smll.201503316

In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging

Li Shang
, Linxiao Yang
, Haixia Wang
, Gerd Ulrich Nienhaus

Karlsruhe Institute of Technology
University of Illinois at Urbana-Champaign

科研成果: 期刊稿件 › 文章 › 同行评审

31 引用（Scopus）

摘要

FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.

源语言	英语
页（从-至）	868-873
页数	6
期刊	Small
卷	12
期	7
DOI	https://doi.org/10.1002/smll.201503316
出版状态	已出版 - 17 2月 2016
已对外发布	是

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abstract = "FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.",

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author = "Li Shang and Linxiao Yang and Haixia Wang and Nienhaus, \{Gerd Ulrich\}",

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AU - Wang, Haixia

AU - Nienhaus, Gerd Ulrich

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AB - FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.

KW - fluorescence lifetime imaging microscopy

KW - live cells

KW - luminescent probes

KW - nanoparticles

KW - quantum dots

UR - https://www.scopus.com/pages/publications/84958119534

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In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging

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