Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis

Lu Yan; Guanwen Liu; Xinglong Wang; Chunmei Jiang; Dongyan Shao; Junling Shi

Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis

Lu Yan
, Guanwen Liu
, Xinglong Wang
, Chunmei Jiang
, Dongyan Shao
, Junling Shi

生命学院

Northwestern Polytechnical University Xian
Northwest Agriculture and Forestry University

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

1 引用（Scopus）

摘要

Wound healing is an intricate and orchestrated process composed of inflammation, tissue formation, and remodeling phases, and is delayed in some cases, such as diabetes. Although some drugs have been applied to clinical use, the availability of drugs to promote the wound healing is required. Lipopeptides produced by Bacillus subtilis are famous for their antimicrobial activities, however, no report of lipopeptides has been found on affecting wound healing. The aim of our study is to determine the possibility of lipopeptides on wound healing. Results indicated that lipopeptides produced by B. subtilis markedly accelerated wound healing on the rabbit skin, and regulated inflammation reaction at the wound site by increasing the expression of TGF-β2 and IL-6. In conclusion, the function of lipopeptides might indicate the possibility of its clinical use for wound therapy.

源语言	英语
主期刊名	3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019
出版商	VDE Verlag GmbH
页	521-524
页数	4
ISBN（电子版）	9783800750269
出版状态	已出版 - 2019
活动	3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019 - Hangzhou, 中国期限: 20 7月 2019 → 22 7月 2019

丛书

姓名	3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019

会议

会议	3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019
国家/地区	中国
市	Hangzhou
时期	20/07/19 → 22/07/19

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

其它文件与链接

链接到 Scopus 的出版物

引用此

Yan, L., Liu, G., Wang, X., Jiang, C., Shao, D., & Shi, J. (2019). Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis. 在 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019 (页码 521-524). (3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019). VDE Verlag GmbH.

Yan, Lu ; Liu, Guanwen ; Wang, Xinglong 等. / Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis. 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019. VDE Verlag GmbH, 2019. 页码 521-524 (3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019).

@inproceedings{42f0d27570754133903e48d3df140254,

title = "Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis",

abstract = "Wound healing is an intricate and orchestrated process composed of inflammation, tissue formation, and remodeling phases, and is delayed in some cases, such as diabetes. Although some drugs have been applied to clinical use, the availability of drugs to promote the wound healing is required. Lipopeptides produced by Bacillus subtilis are famous for their antimicrobial activities, however, no report of lipopeptides has been found on affecting wound healing. The aim of our study is to determine the possibility of lipopeptides on wound healing. Results indicated that lipopeptides produced by B. subtilis markedly accelerated wound healing on the rabbit skin, and regulated inflammation reaction at the wound site by increasing the expression of TGF-β2 and IL-6. In conclusion, the function of lipopeptides might indicate the possibility of its clinical use for wound therapy.",

author = "Lu Yan and Guanwen Liu and Xinglong Wang and Chunmei Jiang and Dongyan Shao and Junling Shi",

note = "Publisher Copyright: {\textcopyright} VDE VERLAG GMBH · Berlin · Offenbach.; 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019 ; Conference date: 20-07-2019 Through 22-07-2019",

year = "2019",

language = "英语",

series = "3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019",

publisher = "VDE Verlag GmbH",

pages = "521--524",

booktitle = "3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019",

}

Yan, L, Liu, G, Wang, X, Jiang, C, Shao, D & Shi, J 2019, Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis. 在 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019. 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019, VDE Verlag GmbH, 页码 521-524, 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019, Hangzhou, 中国, 20/07/19.

Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis. / Yan, Lu; Liu, Guanwen; Wang, Xinglong 等.
3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019. VDE Verlag GmbH, 2019. 页码 521-524 (3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019).

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

TY - GEN

T1 - Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis

AU - Yan, Lu

AU - Liu, Guanwen

AU - Wang, Xinglong

AU - Jiang, Chunmei

AU - Shao, Dongyan

AU - Shi, Junling

PY - 2019

Y1 - 2019

N2 - Wound healing is an intricate and orchestrated process composed of inflammation, tissue formation, and remodeling phases, and is delayed in some cases, such as diabetes. Although some drugs have been applied to clinical use, the availability of drugs to promote the wound healing is required. Lipopeptides produced by Bacillus subtilis are famous for their antimicrobial activities, however, no report of lipopeptides has been found on affecting wound healing. The aim of our study is to determine the possibility of lipopeptides on wound healing. Results indicated that lipopeptides produced by B. subtilis markedly accelerated wound healing on the rabbit skin, and regulated inflammation reaction at the wound site by increasing the expression of TGF-β2 and IL-6. In conclusion, the function of lipopeptides might indicate the possibility of its clinical use for wound therapy.

AB - Wound healing is an intricate and orchestrated process composed of inflammation, tissue formation, and remodeling phases, and is delayed in some cases, such as diabetes. Although some drugs have been applied to clinical use, the availability of drugs to promote the wound healing is required. Lipopeptides produced by Bacillus subtilis are famous for their antimicrobial activities, however, no report of lipopeptides has been found on affecting wound healing. The aim of our study is to determine the possibility of lipopeptides on wound healing. Results indicated that lipopeptides produced by B. subtilis markedly accelerated wound healing on the rabbit skin, and regulated inflammation reaction at the wound site by increasing the expression of TGF-β2 and IL-6. In conclusion, the function of lipopeptides might indicate the possibility of its clinical use for wound therapy.

UR - https://www.scopus.com/pages/publications/85096511830

M3 - 会议稿件

AN - SCOPUS:85096511830

T3 - 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019

SP - 521

EP - 524

BT - 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019

PB - VDE Verlag GmbH

T2 - 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019

Y2 - 20 July 2019 through 22 July 2019

ER -

Yan L, Liu G, Wang X, Jiang C, Shao D, Shi J. Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis. 在 3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019. VDE Verlag GmbH. 2019. 页码 521-524. (3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019).

Identification and characterization of lipopeptides as a potential wound healing agent produced by Bacillus subtilis

摘要

丛书

会议

联合国可持续发展目标

其它文件与链接

学术指纹

引用此