Development Trend of 3D Printing Bone Tissue Engineering Scaffold Based on Black Phosphorus Nanosheets

With the increasingly serious problem of population aging, the number of patients with bone defects caused by degenerative diseases is gradually increasing, which has brought great pressure to the medical system of various countries. Bone tissue engineering scaffolds made of traditional biomaterials are easy to produce problems such as poor fit, wear and corrosion after repairing bone tissue, especially it is difficult to form bone tissue with biological function. In this paper, the research status of 3D printed bone tissue engineering scaffold technology based on black phosphorus nanosheets (BPNs) is deeply analyzed. It is considered that BPNs have unique advantages and development prospects compared with other traditional bone tissue scaffold materials (such as bioceramics and metal materials). The combination of BPNs and 3D-printed bone tissue engineering scaffolds can overcome the defects of traditional scaffold manufacturing methods and achieve a breakthrough in the personalized, accurate, mechanical strength, pore regulation and spatial structure complexity of scaffolds. This study provides a salutary lesson for the design of 3D printed bone tissue engineering scaffolds and the improvement of antibacterial and stability based on BPNs.