Carbene-Catalyzed Construction of Carbazoles from Enals and 2-Methyl-3-oxoacetate Indoles

Dehai Liu; Yaru Gao; Jie Huang; Zhenqian Fu; Wei Huang

doi:10.1021/acs.joc.8b02532

Carbene-Catalyzed Construction of Carbazoles from Enals and 2-Methyl-3-oxoacetate Indoles

Dehai Liu
, Yaru Gao
, Jie Huang
, Zhenqian Fu
, Wei Huang

柔性电子研究院

Nanjing Tech University

科研成果: 期刊稿件 › 文章 › 同行评审

33 引用（Scopus）

摘要

Direct and rapid construction of carbazoles has been successfully developed via carbene-catalyzed oxidative formal [4 + 2] annulation of enals with 2-methyl-3-oxoacetate indoles. This metal-free reaction features a broad substrate scope, features good functional-group tolerance, proceeds under mild conditions, and can be easily scaled up.

源语言	英语
页（从-至）	14210-14217
页数	8
期刊	Journal of Organic Chemistry
卷	83
期	22
DOI	https://doi.org/10.1021/acs.joc.8b02532
出版状态	已出版 - 16 11月 2018

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10.1021/acs.joc.8b02532

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abstract = "Direct and rapid construction of carbazoles has been successfully developed via carbene-catalyzed oxidative formal [4 + 2] annulation of enals with 2-methyl-3-oxoacetate indoles. This metal-free reaction features a broad substrate scope, features good functional-group tolerance, proceeds under mild conditions, and can be easily scaled up.",

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AU - Fu, Zhenqian

AU - Huang, Wei

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AB - Direct and rapid construction of carbazoles has been successfully developed via carbene-catalyzed oxidative formal [4 + 2] annulation of enals with 2-methyl-3-oxoacetate indoles. This metal-free reaction features a broad substrate scope, features good functional-group tolerance, proceeds under mild conditions, and can be easily scaled up.

UR - https://www.scopus.com/pages/publications/85056178701

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Carbene-Catalyzed Construction of Carbazoles from Enals and 2-Methyl-3-oxoacetate Indoles

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