Analyzing factors involved in the HPO-based semantic similarity calculation

Jiajie Peng; Qianqian Li; Bolin Chen; Jialu Hu; Xuequn Shang

doi:10.1109/BIBM.2016.7822766

Analyzing factors involved in the HPO-based semantic similarity calculation

Jiajie Peng
, Qianqian Li
, Bolin Chen
, Jialu Hu
, Xuequn Shang

计算机学院

Northwestern Polytechnical University Xian

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

摘要

Although disease diagnosis have greatly benefited from next generation sequencing technologies, it is still difficult to make the right diagnosis based on purely sequencing technologies for many diseases with complex phenotypes and high genetic heterogeneity. Recently, calculating Human Phenotype Ontology (HPO)-based phenotype semantic similarity has contributed a lot for completing disease diagnosis. However, factors which affect the accuracy of HPO-based semantic similarity have not been evaluated systematically. In this study, we propose a new framework called HPOFactor to evaluate these factors.

源语言	英语
主期刊名	Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016
编辑	Kevin Burrage, Qian Zhu, Yunlong Liu, Tianhai Tian, Yadong Wang, Xiaohua Tony Hu, Qinghua Jiang, Jiangning Song, Shinichi Morishita, Kevin Burrage, Guohua Wang
出版商	Institute of Electrical and Electronics Engineers Inc.
页	1653-1656
页数	4
ISBN（电子版）	9781509016105
DOI	https://doi.org/10.1109/BIBM.2016.7822766
出版状态	已出版 - 17 1月 2017
活动	2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016 - Shenzhen, 中国期限: 15 12月 2016 → 18 12月 2016

出版系列

姓名	Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016

会议

会议	2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016
国家/地区	中国
市	Shenzhen
时期	15/12/16 → 18/12/16

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

访问文件

10.1109/BIBM.2016.7822766

其它文件与链接

链接到 Scopus 的出版物

引用此

Peng, J., Li, Q., Chen, B., Hu, J., & Shang, X. (2017). Analyzing factors involved in the HPO-based semantic similarity calculation. 在 K. Burrage, Q. Zhu, Y. Liu, T. Tian, Y. Wang, X. T. Hu, Q. Jiang, J. Song, S. Morishita, K. Burrage, & G. Wang (编辑), Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016 (页码 1653-1656). 文章 7822766 (Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BIBM.2016.7822766

Peng, Jiajie ; Li, Qianqian ; Chen, Bolin 等. / Analyzing factors involved in the HPO-based semantic similarity calculation. Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016. 编辑 / Kevin Burrage ; Qian Zhu ; Yunlong Liu ; Tianhai Tian ; Yadong Wang ; Xiaohua Tony Hu ; Qinghua Jiang ; Jiangning Song ; Shinichi Morishita ; Kevin Burrage ; Guohua Wang. Institute of Electrical and Electronics Engineers Inc., 2017. 页码 1653-1656 (Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016).

@inproceedings{e0a534d4fe4c4c94a13fe17f4488d48c,

title = "Analyzing factors involved in the HPO-based semantic similarity calculation",

abstract = "Although disease diagnosis have greatly benefited from next generation sequencing technologies, it is still difficult to make the right diagnosis based on purely sequencing technologies for many diseases with complex phenotypes and high genetic heterogeneity. Recently, calculating Human Phenotype Ontology (HPO)-based phenotype semantic similarity has contributed a lot for completing disease diagnosis. However, factors which affect the accuracy of HPO-based semantic similarity have not been evaluated systematically. In this study, we propose a new framework called HPOFactor to evaluate these factors.",

author = "Jiajie Peng and Qianqian Li and Bolin Chen and Jialu Hu and Xuequn Shang",

note = "Publisher Copyright: {\textcopyright} 2016 IEEE.; 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016 ; Conference date: 15-12-2016 Through 18-12-2016",

year = "2017",

month = jan,

day = "17",

doi = "10.1109/BIBM.2016.7822766",

language = "英语",

series = "Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "1653--1656",

editor = "Kevin Burrage and Qian Zhu and Yunlong Liu and Tianhai Tian and Yadong Wang and Hu, \{Xiaohua Tony\} and Qinghua Jiang and Jiangning Song and Shinichi Morishita and Kevin Burrage and Guohua Wang",

booktitle = "Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016",

}

Peng, J, Li, Q, Chen, B, Hu, J & Shang, X 2017, Analyzing factors involved in the HPO-based semantic similarity calculation. 在 K Burrage, Q Zhu, Y Liu, T Tian, Y Wang, XT Hu, Q Jiang, J Song, S Morishita, K Burrage & G Wang (编辑), Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016., 7822766, Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016, Institute of Electrical and Electronics Engineers Inc., 页码 1653-1656, 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016, Shenzhen, 中国, 15/12/16. https://doi.org/10.1109/BIBM.2016.7822766

Analyzing factors involved in the HPO-based semantic similarity calculation. / Peng, Jiajie; Li, Qianqian; Chen, Bolin 等.
Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016. 编辑 / Kevin Burrage; Qian Zhu; Yunlong Liu; Tianhai Tian; Yadong Wang; Xiaohua Tony Hu; Qinghua Jiang; Jiangning Song; Shinichi Morishita; Kevin Burrage; Guohua Wang. Institute of Electrical and Electronics Engineers Inc., 2017. 页码 1653-1656 7822766 (Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016).

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

TY - GEN

T1 - Analyzing factors involved in the HPO-based semantic similarity calculation

AU - Peng, Jiajie

AU - Li, Qianqian

AU - Chen, Bolin

AU - Hu, Jialu

AU - Shang, Xuequn

PY - 2017/1/17

Y1 - 2017/1/17

N2 - Although disease diagnosis have greatly benefited from next generation sequencing technologies, it is still difficult to make the right diagnosis based on purely sequencing technologies for many diseases with complex phenotypes and high genetic heterogeneity. Recently, calculating Human Phenotype Ontology (HPO)-based phenotype semantic similarity has contributed a lot for completing disease diagnosis. However, factors which affect the accuracy of HPO-based semantic similarity have not been evaluated systematically. In this study, we propose a new framework called HPOFactor to evaluate these factors.

AB - Although disease diagnosis have greatly benefited from next generation sequencing technologies, it is still difficult to make the right diagnosis based on purely sequencing technologies for many diseases with complex phenotypes and high genetic heterogeneity. Recently, calculating Human Phenotype Ontology (HPO)-based phenotype semantic similarity has contributed a lot for completing disease diagnosis. However, factors which affect the accuracy of HPO-based semantic similarity have not been evaluated systematically. In this study, we propose a new framework called HPOFactor to evaluate these factors.

UR - https://www.scopus.com/pages/publications/85013301471

U2 - 10.1109/BIBM.2016.7822766

DO - 10.1109/BIBM.2016.7822766

M3 - 会议稿件

AN - SCOPUS:85013301471

T3 - Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016

SP - 1653

EP - 1656

BT - Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016

A2 - Burrage, Kevin

A2 - Zhu, Qian

A2 - Liu, Yunlong

A2 - Tian, Tianhai

A2 - Wang, Yadong

A2 - Hu, Xiaohua Tony

A2 - Jiang, Qinghua

A2 - Song, Jiangning

A2 - Morishita, Shinichi

A2 - Burrage, Kevin

A2 - Wang, Guohua

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016

Y2 - 15 December 2016 through 18 December 2016

ER -

Peng J, Li Q, Chen B, Hu J, Shang X. Analyzing factors involved in the HPO-based semantic similarity calculation. 在 Burrage K, Zhu Q, Liu Y, Tian T, Wang Y, Hu XT, Jiang Q, Song J, Morishita S, Burrage K, Wang G, 编辑, Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016. Institute of Electrical and Electronics Engineers Inc. 2017. 页码 1653-1656. 7822766. (Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016). doi: 10.1109/BIBM.2016.7822766

Analyzing factors involved in the HPO-based semantic similarity calculation

摘要

出版系列

会议

联合国可持续发展目标

访问文件

其它文件与链接

学术指纹

引用此