A Novel Single Cell Culture Chip Based on One-Step Method

Fang Ye; Meiying He; Jin Xie; Li Xie; Honglong Chang; Weizheng Yuan

doi:10.1051/jnwpu/20183610132

A Novel Single Cell Culture Chip Based on One-Step Method

Fang Ye
, Meiying He
, Jin Xie
, Li Xie
, Honglong Chang
, Weizheng Yuan

Northwestern Polytechnical University Xian
China Academy of Engineering Physics

科研成果: 期刊稿件 › 文章 › 同行评审

摘要

More and more basic biology research focus on the single cell level. However, the way to fabricate a chemically patterned surface exist some questions such as complex fabrication process, graphic quality puzzle and so on. In this paper, we present a One-Step method based on Poly 2-hydroxyethyl methacrylate (PolyHEMA) and micromolding in capillaries (MIMIC) technology to fabricate single cell culture chip. Experimental evidence indicates that the integrity and stability of the PolyHEMA pattern can perfectly satisfy the need of long-term cell culture.

源语言	英语
页（从-至）	132-138
页数	7
期刊	Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University
卷	36
期	1
DOI	https://doi.org/10.1051/jnwpu/20183610132
出版状态	已出版 - 2月 2018

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10.1051/jnwpu/20183610132

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abstract = "More and more basic biology research focus on the single cell level. However, the way to fabricate a chemically patterned surface exist some questions such as complex fabrication process, graphic quality puzzle and so on. In this paper, we present a One-Step method based on Poly 2-hydroxyethyl methacrylate (PolyHEMA) and micromolding in capillaries (MIMIC) technology to fabricate single cell culture chip. Experimental evidence indicates that the integrity and stability of the PolyHEMA pattern can perfectly satisfy the need of long-term cell culture.",

keywords = "MIMIC, Micropattern, PolyHEMA, Single cell culture",

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AU - Chang, Honglong

AU - Yuan, Weizheng

PY - 2018/2

Y1 - 2018/2

N2 - More and more basic biology research focus on the single cell level. However, the way to fabricate a chemically patterned surface exist some questions such as complex fabrication process, graphic quality puzzle and so on. In this paper, we present a One-Step method based on Poly 2-hydroxyethyl methacrylate (PolyHEMA) and micromolding in capillaries (MIMIC) technology to fabricate single cell culture chip. Experimental evidence indicates that the integrity and stability of the PolyHEMA pattern can perfectly satisfy the need of long-term cell culture.

AB - More and more basic biology research focus on the single cell level. However, the way to fabricate a chemically patterned surface exist some questions such as complex fabrication process, graphic quality puzzle and so on. In this paper, we present a One-Step method based on Poly 2-hydroxyethyl methacrylate (PolyHEMA) and micromolding in capillaries (MIMIC) technology to fabricate single cell culture chip. Experimental evidence indicates that the integrity and stability of the PolyHEMA pattern can perfectly satisfy the need of long-term cell culture.

KW - MIMIC

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KW - Single cell culture

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JO - Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University

JF - Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University

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A Novel Single Cell Culture Chip Based on One-Step Method

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