A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings

Zhejun Guo; Bowen Ji; Longchun Wang; Bin Yang; Wei Wang; Jingquan Liu

doi:10.1109/MEMS46641.2020.9056263

A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings

Zhejun Guo
, Bowen Ji
, Longchun Wang
, Bin Yang
, Wei Wang
, Jingquan Liu

Shanghai Jiao Tong University
Peking University

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

9 引用（Scopus）

摘要

This paper reports on a flexible and stretchable neural probe based on polyimide (PI) which has excellent robustness and biocompatibility. For the first time, the kirigami structure is designed in the flexible probe substrate, and the composite Young's modulus of the flexible probe decreases from 2.5Gpa to 2KPa which will enhance adaptability of the probe in the micromotion of the brain tissue. Hundreds of cyclic stretching tests verified the flexibility and effectiveness of the neural probe. In addition, it has been proved in vitro that the probe can be easily implanted into the tissue by steel needle.

源语言	英语
主期刊名	33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020
出版商	Institute of Electrical and Electronics Engineers Inc.
页	350-353
页数	4
ISBN（电子版）	9781728135809
DOI	https://doi.org/10.1109/MEMS46641.2020.9056263
出版状态	已出版 - 1月 2020
已对外发布	是
活动	33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020 - Vancouver, 加拿大期限: 18 1月 2020 → 22 1月 2020

丛书

姓名	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
卷	2020-January
ISSN（印刷版）	1084-6999

会议

会议	33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020
国家/地区	加拿大
市	Vancouver
时期	18/01/20 → 22/01/20

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10.1109/MEMS46641.2020.9056263

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引用此

Guo, Z., Ji, B., Wang, L., Yang, B., Wang, W., & Liu, J. (2020). A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings. 在 33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020 (页码 350-353). 期刊论文 9056263 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); 卷 2020-January). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMS46641.2020.9056263

Guo, Zhejun ; Ji, Bowen ; Wang, Longchun 等. / A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings. 33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020. Institute of Electrical and Electronics Engineers Inc., 2020. 页码 350-353 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

@inproceedings{aac3b9df84164a75a1bd0a1ecb4bfbd6,

title = "A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings",

abstract = "This paper reports on a flexible and stretchable neural probe based on polyimide (PI) which has excellent robustness and biocompatibility. For the first time, the kirigami structure is designed in the flexible probe substrate, and the composite Young's modulus of the flexible probe decreases from 2.5Gpa to 2KPa which will enhance adaptability of the probe in the micromotion of the brain tissue. Hundreds of cyclic stretching tests verified the flexibility and effectiveness of the neural probe. In addition, it has been proved in vitro that the probe can be easily implanted into the tissue by steel needle.",

author = "Zhejun Guo and Bowen Ji and Longchun Wang and Bin Yang and Wei Wang and Jingquan Liu",

note = "Publisher Copyright: {\textcopyright} 2020 IEEE.; 33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020 ; Conference date: 18-01-2020 Through 22-01-2020",

year = "2020",

month = jan,

doi = "10.1109/MEMS46641.2020.9056263",

language = "英语",

series = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "350--353",

booktitle = "33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020",

}

Guo, Z, Ji, B, Wang, L, Yang, B, Wang, W & Liu, J 2020, A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings. 在 33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020., 9056263, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), 卷 2020-January, Institute of Electrical and Electronics Engineers Inc., 页码 350-353, 33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020, Vancouver, 加拿大, 18/01/20. https://doi.org/10.1109/MEMS46641.2020.9056263

A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings. / Guo, Zhejun; Ji, Bowen; Wang, Longchun 等.
33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020. Institute of Electrical and Electronics Engineers Inc., 2020. 页码 350-353 9056263 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); 卷 2020-January).

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

TY - GEN

T1 - A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings

AU - Guo, Zhejun

AU - Ji, Bowen

AU - Wang, Longchun

AU - Yang, Bin

AU - Wang, Wei

AU - Liu, Jingquan

PY - 2020/1

Y1 - 2020/1

N2 - This paper reports on a flexible and stretchable neural probe based on polyimide (PI) which has excellent robustness and biocompatibility. For the first time, the kirigami structure is designed in the flexible probe substrate, and the composite Young's modulus of the flexible probe decreases from 2.5Gpa to 2KPa which will enhance adaptability of the probe in the micromotion of the brain tissue. Hundreds of cyclic stretching tests verified the flexibility and effectiveness of the neural probe. In addition, it has been proved in vitro that the probe can be easily implanted into the tissue by steel needle.

AB - This paper reports on a flexible and stretchable neural probe based on polyimide (PI) which has excellent robustness and biocompatibility. For the first time, the kirigami structure is designed in the flexible probe substrate, and the composite Young's modulus of the flexible probe decreases from 2.5Gpa to 2KPa which will enhance adaptability of the probe in the micromotion of the brain tissue. Hundreds of cyclic stretching tests verified the flexibility and effectiveness of the neural probe. In addition, it has been proved in vitro that the probe can be easily implanted into the tissue by steel needle.

UR - https://www.scopus.com/pages/publications/85083201284

U2 - 10.1109/MEMS46641.2020.9056263

DO - 10.1109/MEMS46641.2020.9056263

M3 - 会议稿件

AN - SCOPUS:85083201284

T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

SP - 350

EP - 353

BT - 33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020

Y2 - 18 January 2020 through 22 January 2020

ER -

Guo Z, Ji B, Wang L, Yang B, Wang W, Liu J. A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings. 在 33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020. Institute of Electrical and Electronics Engineers Inc. 2020. 页码 350-353. 9056263. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMS46641.2020.9056263

A Flexible and Stretchable Kirigami-Inspired Implantable Neural Probe with Floating Microsites for Electrophysiology Recordings

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