The Construction of Stimulus-responsive Film Electrode by the Cu-catalyzed Radical Polymerization and its Application in Multi-valued Biologic Systems

N-isopropylacrylamide was polymerized on the surface of copper-plated carbon paper electrode by a novel redox initiation system composed of persulfate and copper nanoparticles, and the PNIPAAm−Cu NPs@CP film electrode was obtained. Cyclic voltammetry (CV) results showed that the electrode exhibits a reversible temperature, pH and glucose switchable electrical signal response through the ferrocene carboxylic acid (Fc(COOH)). With this basis, a 4-current output logic gate system consisting of 3-response inputs of temperature, pH, and glucose was fabricated and a corresponding logic circuit for 3-input/4-output ports was established. This work might provide a new avenue for the development of multi-valued biologic systems.