System-level modeling and simulation for chip-based capillary electrophoresis

To develop computer aided design software of microfluidic chip system, the parameterized behavior model of chip-based capillary electrophoresis was established by using the system-level modeling method. The length of microchannel and the broadening of band are main factors that have influence directly on the electrophoretic seperation chips. Compared with the finite element model, the speed of simulation based on the established model enhances up 100 times with a relative error of 3.8 %. The results show that the chip-based separating capillary electrophoresis behavior model we proposed can evaluate more speedily, more effectively the properties of the system without reduction of its simulate precision.