Slip behavior evolution mechanisms of nanoconfined glycerol-water solution with effects of surface physicochemical properties

Mastering solid-liquid interface slip is paramount for enhancing energy efficiency in nanofluidic systems, yet the evolution pathways governed by surface physicochemical properties remain poorly understood. Here, via molecular dynamics simulations, we unveil how interfacial chemistry and topography competitively orchestrate the slip evolution of glycerol-water solutions on four model surfaces (Fe₂O₃, graphene, DLC, and PTFE). We identify three distinct slip regimes: wall slip (superlubricity), partial interface slip, and intralayer shear (high friction dissipation). The slip evolution follows divergent paths: chemical affinity enforces intralayer shear on Fe₂O₃; wettability reversal triggers transitions on graphene and DLC; and nanoscale physical pinning overrides intrinsic hydrophobicity to promote intralayer shear on PTFE. Dynamic strain localization maps and slip phase diagram provide quantitative, real-space validation of these interfacial constraints. The constructed competition intensity index I ( C ) moves beyond phenomenological observation to establish a unified competition framework among adsorption ordering, wettability reversal, and physical pinning, offering general design principles for manipulating interfacial transport in advanced nanotechnologies.