Palladium-catalyzed cross-couplings of unsaturated halides bearing relatively acidic hydrogen atoms with organozinc reagents

Zhibing Dong; Georg Manolikakes; Jinshan Li; Paul Knochel

doi:10.1055/s-0028-1083286

Palladium-catalyzed cross-couplings of unsaturated halides bearing relatively acidic hydrogen atoms with organozinc reagents

Zhibing Dong, Georg Manolikakes, Jinshan Li, Paul Knochel

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

A wide range of polyfunctional aryl, heteroaryl, alkyl, and benzylic zinc reagents were coupled with unsaturated aryl halides bearing an acidic NH or OH proton, using palladium(II) acetate (1 mol%), and S-Phos (2 mol%) as catalyst without the need of protecting groups.

Original language	English
Pages (from-to)	681-686
Number of pages	6
Journal	Synthesis
Issue number	4
DOIs	https://doi.org/10.1055/s-0028-1083286
State	Published - 2009
Externally published	Yes

Keywords

Cross-coupling
Functionalized zinc reagents
Palladium catalysis
Polyfunctional biaryls

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10.1055/s-0028-1083286

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title = "Palladium-catalyzed cross-couplings of unsaturated halides bearing relatively acidic hydrogen atoms with organozinc reagents",

abstract = "A wide range of polyfunctional aryl, heteroaryl, alkyl, and benzylic zinc reagents were coupled with unsaturated aryl halides bearing an acidic NH or OH proton, using palladium(II) acetate (1 mol%), and S-Phos (2 mol%) as catalyst without the need of protecting groups.",

keywords = "Cross-coupling, Functionalized zinc reagents, Palladium catalysis, Polyfunctional biaryls",

author = "Zhibing Dong and Georg Manolikakes and Jinshan Li and Paul Knochel",

year = "2009",

doi = "10.1055/s-0028-1083286",

language = "英语",

pages = "681--686",

journal = "Synthesis",

issn = "0039-7881",

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T1 - Palladium-catalyzed cross-couplings of unsaturated halides bearing relatively acidic hydrogen atoms with organozinc reagents

AU - Dong, Zhibing

AU - Manolikakes, Georg

AU - Li, Jinshan

AU - Knochel, Paul

PY - 2009

Y1 - 2009

N2 - A wide range of polyfunctional aryl, heteroaryl, alkyl, and benzylic zinc reagents were coupled with unsaturated aryl halides bearing an acidic NH or OH proton, using palladium(II) acetate (1 mol%), and S-Phos (2 mol%) as catalyst without the need of protecting groups.

AB - A wide range of polyfunctional aryl, heteroaryl, alkyl, and benzylic zinc reagents were coupled with unsaturated aryl halides bearing an acidic NH or OH proton, using palladium(II) acetate (1 mol%), and S-Phos (2 mol%) as catalyst without the need of protecting groups.

KW - Cross-coupling

KW - Functionalized zinc reagents

KW - Palladium catalysis

KW - Polyfunctional biaryls

UR - http://www.scopus.com/inward/record.url?scp=63849336084&partnerID=8YFLogxK

U2 - 10.1055/s-0028-1083286

DO - 10.1055/s-0028-1083286

M3 - 文章

AN - SCOPUS:63849336084

SN - 0039-7881

SP - 681

EP - 686

JO - Synthesis

JF - Synthesis

IS - 4

ER -

Palladium-catalyzed cross-couplings of unsaturated halides bearing relatively acidic hydrogen atoms with organozinc reagents

Abstract

Keywords

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