On-chip enantioselective refractive-index sensing enabled by chiral metal-organic frameworks

Peng Qin; Ruyuan Zhou; Xinghang Ma; Xuetao Gan

doi:10.1364/PRJ.583977

On-chip enantioselective refractive-index sensing enabled by chiral metal-organic frameworks

Peng Qin
, Ruyuan Zhou
, Xinghang Ma
, Xuetao Gan

School of Microelectronics

Northwestern Polytechnical University Xian

Research output: Contribution to journal › Article › peer-review

Abstract

High-sensitivity identification and quantification of chiral molecules are vital in life sciences and pharmaceutical analysis. We demonstrate an on-chip chiral sensing platform based on microring resonator arrays functionalized with chiral Cu₂(DCam)₂(dabco) metal-organic frameworks (MOFs)· The layer-by-layer-assembled MOF films enable enantioselective adsorption of R - and S -limonene through synergistic chiral pore and Cu-site interactions.

Original language	English
Pages (from-to)	2298-2305
Number of pages	8
Journal	Photonics Research
Volume	14
Issue number	5
DOIs	https://doi.org/10.1364/PRJ.583977
State	Published - May 2026

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title = "On-chip enantioselective refractive-index sensing enabled by chiral metal-organic frameworks",

abstract = "High-sensitivity identification and quantification of chiral molecules are vital in life sciences and pharmaceutical analysis. We demonstrate an on-chip chiral sensing platform based on microring resonator arrays functionalized with chiral Cu2(DCam)2(dabco) metal-organic frameworks (MOFs)· The layer-by-layer-assembled MOF films enable enantioselective adsorption of R - and S -limonene through synergistic chiral pore and Cu-site interactions.",

author = "Peng Qin and Ruyuan Zhou and Xinghang Ma and Xuetao Gan",

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doi = "10.1364/PRJ.583977",

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AU - Qin, Peng

AU - Zhou, Ruyuan

AU - Ma, Xinghang

AU - Gan, Xuetao

PY - 2026/5

Y1 - 2026/5

N2 - High-sensitivity identification and quantification of chiral molecules are vital in life sciences and pharmaceutical analysis. We demonstrate an on-chip chiral sensing platform based on microring resonator arrays functionalized with chiral Cu2(DCam)2(dabco) metal-organic frameworks (MOFs)· The layer-by-layer-assembled MOF films enable enantioselective adsorption of R - and S -limonene through synergistic chiral pore and Cu-site interactions.

AB - High-sensitivity identification and quantification of chiral molecules are vital in life sciences and pharmaceutical analysis. We demonstrate an on-chip chiral sensing platform based on microring resonator arrays functionalized with chiral Cu2(DCam)2(dabco) metal-organic frameworks (MOFs)· The layer-by-layer-assembled MOF films enable enantioselective adsorption of R - and S -limonene through synergistic chiral pore and Cu-site interactions.

UR - https://www.scopus.com/pages/publications/105043978707

U2 - 10.1364/PRJ.583977

DO - 10.1364/PRJ.583977

M3 - 文章

AN - SCOPUS:105043978707

SN - 2327-9125

VL - 14

SP - 2298

EP - 2305

JO - Photonics Research

JF - Photonics Research

IS - 5

ER -

On-chip enantioselective refractive-index sensing enabled by chiral metal-organic frameworks

Abstract

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