TY - JOUR
T1 - Noninvasive photothermal cancer therapy nanoplatforms
T2 - Via integrating nanomaterials and functional polymers
AU - Ban, Qingfu
AU - Bai, Ting
AU - Duan, Xiao
AU - Kong, Jie
N1 - Publisher Copyright:
© 2017 The Royal Society of Chemistry.
PY - 2017/2
Y1 - 2017/2
N2 - In the cutting-edge field of cancer therapy, noninvasive photothermal therapy (PTT) has received great attention because it is considered to overcome the drawbacks of conventional surgery, radiotherapy and chemotherapy of severe body injuries and side effects on the immune system. The construction of PTT therapeutic and theranostic nanoplatforms is the key issue in achieving tumor targeting, imaging and therapy in a synergetic manner. In this review, we focus on the recent advances in constructing PTT therapeutic and theranostic nanoplatforms by integrating nanomaterials and functional polymers. The noninvasive photothermal cancer therapy mechanism and achievement strategies of PTT therapeutic and theranostic nanoplatforms are presented as well as the innovative construction strategies and perspectives for the future. Owing to their high tumor ablation efficiency, biological availability and low- or non-toxicity, PTT therapeutic and theranostic nanoplatforms are promising and emerging in medicine and clinical applications.
AB - In the cutting-edge field of cancer therapy, noninvasive photothermal therapy (PTT) has received great attention because it is considered to overcome the drawbacks of conventional surgery, radiotherapy and chemotherapy of severe body injuries and side effects on the immune system. The construction of PTT therapeutic and theranostic nanoplatforms is the key issue in achieving tumor targeting, imaging and therapy in a synergetic manner. In this review, we focus on the recent advances in constructing PTT therapeutic and theranostic nanoplatforms by integrating nanomaterials and functional polymers. The noninvasive photothermal cancer therapy mechanism and achievement strategies of PTT therapeutic and theranostic nanoplatforms are presented as well as the innovative construction strategies and perspectives for the future. Owing to their high tumor ablation efficiency, biological availability and low- or non-toxicity, PTT therapeutic and theranostic nanoplatforms are promising and emerging in medicine and clinical applications.
UR - http://www.scopus.com/inward/record.url?scp=85011067215&partnerID=8YFLogxK
U2 - 10.1039/c6bm00600k
DO - 10.1039/c6bm00600k
M3 - 文献综述
C2 - 27990534
AN - SCOPUS:85011067215
SN - 2047-4830
VL - 5
SP - 190
EP - 210
JO - Biomaterials Science
JF - Biomaterials Science
IS - 2
ER -