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Monodispersed nanoparticles of conjugated polyelectrolyte brush with high charge density for rapid, specific and label-free detection of tumor marker

  • Xingfen Liu
  • , Lin Shi
  • , Zhiyong Zhang
  • , Quli Fan
  • , Yanqin Huang
  • , Shao Su
  • , Chunhai Fan
  • , Lianhui Wang
  • , Wei Huang
  • Nanjing University of Posts and Telecommunications
  • Chinese Academy of Sciences
  • Nanjing Tech University

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Highly charged nanoparticles of a conjugated polyelectrolyte brush were used to sense the human α-fetoprotein (AFP) by observing selective superquenching in several minutes. The unique property of nanoparticles that the self-aggregation causes an unchanged or enhanced fluorescence can reduce the interference from non-target substance significantly.

Original languageEnglish
Pages (from-to)1842-1846
Number of pages5
JournalAnalyst
Volume140
Issue number6
DOIs
StatePublished - 21 Mar 2015
Externally publishedYes

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