Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan

Zhenming Lü; Li Gong; Yandong Ren; Yongjiu Chen; Zhongkai Wang; Liqin Liu; Haorong Li; Xianqing Chen; Zhenzhu Li; Hairong Luo; Hui Jiang; Yan Zeng; Yifan Wang; Kun Wang; Chen Zhang; Haifeng Jiang; Wenting Wan; Yanli Qin; Jianshe Zhang; Liang Zhu; Wei Shi; Shunping He; Bingyu Mao; Wen Wang; Xiaoyu Kong; Yongxin Li

doi:10.1038/s41588-021-00836-9

Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan

Zhenming Lü, Li Gong, Yandong Ren, Yongjiu Chen, Zhongkai Wang, Liqin Liu, Haorong Li, Xianqing Chen, Zhenzhu Li, Hairong Luo, Hui Jiang, Yan Zeng, Yifan Wang, Kun Wang, Chen Zhang, Haifeng Jiang, Wenting Wan, Yanli Qin, Jianshe Zhang, Liang ZhuWei Shi, Shunping He, Bingyu Mao, Wen Wang, Xiaoyu Kong, Yongxin Li

School of Ecology and Environment

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

The evolutionary and genetic origins of the specialized body plan of flatfish are largely unclear. We analyzed the genomes of 11 flatfish species representing 9 of the 14 Pleuronectiforme families and conclude that Pleuronectoidei and Psettodoidei do not form a monophyletic group, suggesting independent origins from different percoid ancestors. Genomic and transcriptomic data indicate that genes related to WNT and retinoic acid pathways, hampered musculature and reduced lipids might have functioned in the evolution of the specialized body plan of Pleuronectoidei. Evolution of Psettodoidei involved similar but not identical genes. Our work provides valuable resources and insights for understanding the genetic origins of the unusual body plan of flatfishes.

Original language	English
Pages (from-to)	742-751
Number of pages	10
Journal	Nature Genetics
Volume	53
Issue number	5
DOIs	https://doi.org/10.1038/s41588-021-00836-9
State	Published - May 2021

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Lü, Z., Gong, L., Ren, Y., Chen, Y., Wang, Z., Liu, L., Li, H., Chen, X., Li, Z., Luo, H., Jiang, H., Zeng, Y., Wang, Y., Wang, K., Zhang, C., Jiang, H., Wan, W., Qin, Y., Zhang, J., ... Li, Y. (2021). Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan. Nature Genetics, 53(5), 742-751. https://doi.org/10.1038/s41588-021-00836-9

@article{57b46940285640368b32de94c7922339,

title = "Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan",

abstract = "The evolutionary and genetic origins of the specialized body plan of flatfish are largely unclear. We analyzed the genomes of 11 flatfish species representing 9 of the 14 Pleuronectiforme families and conclude that Pleuronectoidei and Psettodoidei do not form a monophyletic group, suggesting independent origins from different percoid ancestors. Genomic and transcriptomic data indicate that genes related to WNT and retinoic acid pathways, hampered musculature and reduced lipids might have functioned in the evolution of the specialized body plan of Pleuronectoidei. Evolution of Psettodoidei involved similar but not identical genes. Our work provides valuable resources and insights for understanding the genetic origins of the unusual body plan of flatfishes.",

author = "Zhenming L{\"u} and Li Gong and Yandong Ren and Yongjiu Chen and Zhongkai Wang and Liqin Liu and Haorong Li and Xianqing Chen and Zhenzhu Li and Hairong Luo and Hui Jiang and Yan Zeng and Yifan Wang and Kun Wang and Chen Zhang and Haifeng Jiang and Wenting Wan and Yanli Qin and Jianshe Zhang and Liang Zhu and Wei Shi and Shunping He and Bingyu Mao and Wen Wang and Xiaoyu Kong and Yongxin Li",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",

year = "2021",

month = may,

doi = "10.1038/s41588-021-00836-9",

language = "英语",

volume = "53",

pages = "742--751",

journal = "Nature Genetics",

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Lü, Z, Gong, L, Ren, Y, Chen, Y, Wang, Z, Liu, L, Li, H, Chen, X, Li, Z, Luo, H, Jiang, H, Zeng, Y, Wang, Y, Wang, K, Zhang, C, Jiang, H, Wan, W, Qin, Y, Zhang, J, Zhu, L, Shi, W, He, S, Mao, B, Wang, W, Kong, X & Li, Y 2021, 'Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan', Nature Genetics, vol. 53, no. 5, pp. 742-751. https://doi.org/10.1038/s41588-021-00836-9

TY - JOUR

T1 - Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan

AU - Lü, Zhenming

AU - Gong, Li

AU - Ren, Yandong

AU - Chen, Yongjiu

AU - Wang, Zhongkai

AU - Liu, Liqin

AU - Li, Haorong

AU - Chen, Xianqing

AU - Li, Zhenzhu

AU - Luo, Hairong

AU - Jiang, Hui

AU - Zeng, Yan

AU - Wang, Yifan

AU - Wang, Kun

AU - Zhang, Chen

AU - Jiang, Haifeng

AU - Wan, Wenting

AU - Qin, Yanli

AU - Zhang, Jianshe

AU - Zhu, Liang

AU - Shi, Wei

AU - He, Shunping

AU - Mao, Bingyu

AU - Wang, Wen

AU - Kong, Xiaoyu

AU - Li, Yongxin

PY - 2021/5

Y1 - 2021/5

N2 - The evolutionary and genetic origins of the specialized body plan of flatfish are largely unclear. We analyzed the genomes of 11 flatfish species representing 9 of the 14 Pleuronectiforme families and conclude that Pleuronectoidei and Psettodoidei do not form a monophyletic group, suggesting independent origins from different percoid ancestors. Genomic and transcriptomic data indicate that genes related to WNT and retinoic acid pathways, hampered musculature and reduced lipids might have functioned in the evolution of the specialized body plan of Pleuronectoidei. Evolution of Psettodoidei involved similar but not identical genes. Our work provides valuable resources and insights for understanding the genetic origins of the unusual body plan of flatfishes.

AB - The evolutionary and genetic origins of the specialized body plan of flatfish are largely unclear. We analyzed the genomes of 11 flatfish species representing 9 of the 14 Pleuronectiforme families and conclude that Pleuronectoidei and Psettodoidei do not form a monophyletic group, suggesting independent origins from different percoid ancestors. Genomic and transcriptomic data indicate that genes related to WNT and retinoic acid pathways, hampered musculature and reduced lipids might have functioned in the evolution of the specialized body plan of Pleuronectoidei. Evolution of Psettodoidei involved similar but not identical genes. Our work provides valuable resources and insights for understanding the genetic origins of the unusual body plan of flatfishes.

UR - https://www.scopus.com/pages/publications/85104850999

U2 - 10.1038/s41588-021-00836-9

DO - 10.1038/s41588-021-00836-9

M3 - 文章

C2 - 33875864

AN - SCOPUS:85104850999

SN - 1061-4036

VL - 53

SP - 742

EP - 751

JO - Nature Genetics

JF - Nature Genetics

IS - 5

ER -

Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan

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