Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells

Qiuyu Gong; Wenjing Qin; Peng Xiao; Xiang Wu; Lin Li; Gaobin Zhang; Renshuai Zhang; Jinpeng Sun; Shao Q. Yao; Wei Huang

doi:10.1039/c9cc07680h

Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells

Qiuyu Gong
, Wenjing Qin
, Peng Xiao
, Xiang Wu
, Lin Li
, Gaobin Zhang
, Renshuai Zhang
, Jinpeng Sun
, Shao Q. Yao
, Wei Huang

Institute of Flexible Electronics

Nanjing Tech University
National University of Singapore
Shandong University

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Herein, as a proof of concept, we developed the first enzymatic VIE fluorogenic probe for protein tyrosine phosphatase 1B (PTP1B). The detection and imaging of PTP1B using VIE in living cells were both realized. Particularly importantly, the designed probe herein provides a guideline and platform for the development of new VIE-based enzymatic probes.

Original language	English
Pages (from-to)	58-61
Number of pages	4
Journal	Chemical Communications
Volume	56
Issue number	1
DOIs	https://doi.org/10.1039/c9cc07680h
State	Published - 2019

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10.1039/c9cc07680h

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title = "Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells",

abstract = "Herein, as a proof of concept, we developed the first enzymatic VIE fluorogenic probe for protein tyrosine phosphatase 1B (PTP1B). The detection and imaging of PTP1B using VIE in living cells were both realized. Particularly importantly, the designed probe herein provides a guideline and platform for the development of new VIE-based enzymatic probes.",

author = "Qiuyu Gong and Wenjing Qin and Peng Xiao and Xiang Wu and Lin Li and Gaobin Zhang and Renshuai Zhang and Jinpeng Sun and Yao, \{Shao Q.\} and Wei Huang",

note = "Publisher Copyright: {\textcopyright} 2019 The Royal Society of Chemistry.",

year = "2019",

doi = "10.1039/c9cc07680h",

language = "英语",

volume = "56",

pages = "58--61",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells

AU - Gong, Qiuyu

AU - Qin, Wenjing

AU - Xiao, Peng

AU - Wu, Xiang

AU - Li, Lin

AU - Zhang, Gaobin

AU - Zhang, Renshuai

AU - Sun, Jinpeng

AU - Yao, Shao Q.

AU - Huang, Wei

PY - 2019

Y1 - 2019

N2 - Herein, as a proof of concept, we developed the first enzymatic VIE fluorogenic probe for protein tyrosine phosphatase 1B (PTP1B). The detection and imaging of PTP1B using VIE in living cells were both realized. Particularly importantly, the designed probe herein provides a guideline and platform for the development of new VIE-based enzymatic probes.

AB - Herein, as a proof of concept, we developed the first enzymatic VIE fluorogenic probe for protein tyrosine phosphatase 1B (PTP1B). The detection and imaging of PTP1B using VIE in living cells were both realized. Particularly importantly, the designed probe herein provides a guideline and platform for the development of new VIE-based enzymatic probes.

UR - https://www.scopus.com/pages/publications/85076696193

U2 - 10.1039/c9cc07680h

DO - 10.1039/c9cc07680h

M3 - 文章

C2 - 31690925

AN - SCOPUS:85076696193

SN - 1359-7345

VL - 56

SP - 58

EP - 61

JO - Chemical Communications

JF - Chemical Communications

IS - 1

ER -

Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells

Abstract

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