In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging

Li Shang; Linxiao Yang; Haixia Wang; Gerd Ulrich Nienhaus

doi:10.1002/smll.201503316

In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging

Li Shang
, Linxiao Yang
, Haixia Wang
, Gerd Ulrich Nienhaus

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.

Original language	English
Pages (from-to)	868-873
Number of pages	6
Journal	Small
Volume	12
Issue number	7
DOIs	https://doi.org/10.1002/smll.201503316
State	Published - 17 Feb 2016
Externally published	Yes

Keywords

fluorescence lifetime imaging microscopy
live cells
luminescent probes
nanoparticles
quantum dots

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10.1002/smll.201503316

Cite this

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title = "In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging",

abstract = "FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.",

keywords = "fluorescence lifetime imaging microscopy, live cells, luminescent probes, nanoparticles, quantum dots",

author = "Li Shang and Linxiao Yang and Haixia Wang and Nienhaus, \{Gerd Ulrich\}",

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AU - Shang, Li

AU - Yang, Linxiao

AU - Wang, Haixia

AU - Nienhaus, Gerd Ulrich

PY - 2016/2/17

Y1 - 2016/2/17

N2 - FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.

AB - FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.

KW - fluorescence lifetime imaging microscopy

KW - live cells

KW - luminescent probes

KW - nanoparticles

KW - quantum dots

UR - https://www.scopus.com/pages/publications/84958119534

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DO - 10.1002/smll.201503316

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AN - SCOPUS:84958119534

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In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging

Abstract

Keywords

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