Hplc analysis of novel anti-cancer agents-illudins and their analogs

E. Brandšteterová; M. J. Kelner; R. Bangell; T. C.Mc Morris; W. Wang

doi:10.1080/10826079308020901

Hplc analysis of novel anti-cancer agents-illudins and their analogs

E. Brandšteterová
, M. J. Kelner
, R. Bangell
, T. C.Mc Morris
, W. Wang

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

High performance liquid chromatography combined with liquid extraction and solid-phase extraction were used for determining the serum concentration of new anticancer drugs. Extraction recoveries were evaluated for wide range of concentrations in serum. Adsorption and reversed-phase chromatographic modes were tested for the separation and drugs determination in model mixtures and actual clinical samples. The HPLC assay developed was applied for farmacokinetic studies of acylfulvene in dog and rats.

Original language	English
Pages (from-to)	115-125
Number of pages	11
Journal	Journal of Liquid Chromatography
Volume	16
Issue number	1
DOIs	https://doi.org/10.1080/10826079308020901
State	Published - 1 Jan 1993
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1080/10826079308020901

Cite this

@article{65905f4f39d542ae93e63e0c03bb508f,

title = "Hplc analysis of novel anti-cancer agents-illudins and their analogs",

abstract = "High performance liquid chromatography combined with liquid extraction and solid-phase extraction were used for determining the serum concentration of new anticancer drugs. Extraction recoveries were evaluated for wide range of concentrations in serum. Adsorption and reversed-phase chromatographic modes were tested for the separation and drugs determination in model mixtures and actual clinical samples. The HPLC assay developed was applied for farmacokinetic studies of acylfulvene in dog and rats.",

author = "E. Brand{\v s}teterov{\'a} and Kelner, \{M. J.\} and R. Bangell and Morris, \{T. C.Mc\} and W. Wang",

year = "1993",

month = jan,

day = "1",

doi = "10.1080/10826079308020901",

language = "英语",

volume = "16",

pages = "115--125",

journal = "Journal of Liquid Chromatography",

issn = "0148-3919",

publisher = "Marcel Dekker Inc.",

number = "1",

}

TY - JOUR

T1 - Hplc analysis of novel anti-cancer agents-illudins and their analogs

AU - Brandšteterová, E.

AU - Kelner, M. J.

AU - Bangell, R.

AU - Morris, T. C.Mc

AU - Wang, W.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - High performance liquid chromatography combined with liquid extraction and solid-phase extraction were used for determining the serum concentration of new anticancer drugs. Extraction recoveries were evaluated for wide range of concentrations in serum. Adsorption and reversed-phase chromatographic modes were tested for the separation and drugs determination in model mixtures and actual clinical samples. The HPLC assay developed was applied for farmacokinetic studies of acylfulvene in dog and rats.

AB - High performance liquid chromatography combined with liquid extraction and solid-phase extraction were used for determining the serum concentration of new anticancer drugs. Extraction recoveries were evaluated for wide range of concentrations in serum. Adsorption and reversed-phase chromatographic modes were tested for the separation and drugs determination in model mixtures and actual clinical samples. The HPLC assay developed was applied for farmacokinetic studies of acylfulvene in dog and rats.

UR - https://www.scopus.com/pages/publications/0027472868

U2 - 10.1080/10826079308020901

DO - 10.1080/10826079308020901

M3 - 文章

AN - SCOPUS:0027472868

SN - 0148-3919

VL - 16

SP - 115

EP - 125

JO - Journal of Liquid Chromatography

JF - Journal of Liquid Chromatography

IS - 1

ER -

Hplc analysis of novel anti-cancer agents-illudins and their analogs

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this