High-resolution multiband polarization epithelial tissue imaging method by sparse representation and fusion

Multiband polarization epithelial tissue imaging is an effective tool to measure tissue's birefringence and structure for quantitative pathology analysis. To discriminate the pathology accurately, high-resolution multiband polarization images are essential. But it is difficult to acquire high-resolution polarization images because of the limitations of imaging systems. The polarization image calculation process can be regarded as image fusion with fixed rules, and multiband polarization images are intrinsically sparse. In this paper, we propose a novel high-resolution multiband polarization image calculation method by utilizing the sparse representation and image fusion method. The multiband images are first represented in the sparse domain and we further introduce total-variation-regularization terms into the sparse representation framework. Then, polarization parameter images are calculated by simultaneous fusion and reconstruction. Higher quality multiband polarization images can be obtained through additional regularization constraint in the fusion process. Extensive experiments validate that the proposed method achieves much better results than many state-of-the-art algorithms in terms of both peak signal-to-noiseratio and visual perception.