Effects of Ultrasound for Bio-Applications

Ultrasound (US), as a non-invasive mechanical wave, has served as a visual tool for medical diagnosis and therapy for echolocation effect, cavitation effect, thermal effect, and generation of reactive oxygen species (ROS) with the aid of sonosensitizers. This review summarizes the history, effects, and biomedical applications of US, and US-assisted cancer therapy is highlighted. The rational combination of US with near-infrared afterglow nanoparticles, anti-tumor prodrugs, and stimuli-responsive nanocarriers, demonstrates the great promise for bioimaging, cancer therapy, and drug delivery, promoting US-related technology in biomedical diagnosis and therapeutics.