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Dry Gongronema latifolium aqueous extract mediated silver nanoparticles by one-step in-situ biosynthesis for antibacterial activities

  • Samson O. Aisida
  • , Kenneth Ugwu
  • , Assumpta C. Nwanya
  • , Paul A. Akpa
  • , I. G. Madiba
  • , A. K.H. Bashir
  • , Subelia Botha
  • , Paul M. Ejikeme
  • , Ting kai Zhao
  • , Ishaq Ahmad
  • , M. Maaza
  • , Fabian I. Ezema
  • University of Nigeria
  • Quaid-I-Azam University
  • iThemba LABS-National Research
  • University of South Africa
  • Northwestern Polytechnical University Xian
  • University of the Western Cape

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

In-situ biosynthesis of silver nanoparticles for antibacterial activities doped with aqueous extract of dry Gongronema Latifolium (DGL) is presented in this work. The absorbance was determined using a UV-Visible analysis with a peak of 428 nm. The obtained particles confirmed by the TEM image analysis were spherical in shape with an average particle size between 5 and 20 nm. A single crystalline phase of FCC was confirmed by the powder. The functional groups showed the phytochemical inherent in the sample. The colloidal solution of DGL-AgNPs with MIC of 10 µg/ml showed a noteworthy functional susceptibility against the bacterial strains, particularly, K. pneumonia with susceptibility greater than gentamicin. Based on these observations, the formulated DGL-AgNPs show strong bactericidal against the pathogens with facile, benign, eco-friendly, biocompatibility and innocuous synthesis procedures. This can serve as an efficient bactericidal agent.

Original languageEnglish
Article number101116
JournalSurfaces and Interfaces
Volume24
DOIs
StatePublished - Jun 2021

Keywords

  • antibacterial activities
  • biosynthesis
  • Gongronema latifolium
  • Silver nanoparticles

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