Abstract
The authors regret the varying number of data points in the bar charts stems from two reasons: 1. The objective of this experiment was to assess the tolerance of encapsulated Lactobacillus rhamnosus in the mouse gastrointestinal tract. Prior to oral administration with L. rhamnosus, mice underwent a 12-h fasting period to ensure undisturbed pH levels in the gastrointestinal tract (as noted in Section 2.7.3). Consequently, during preliminary experiments, some mice exhibited absent colonic contents upon dissection (due to individual variations in excretion rates), preventing the detection of L. rhamnosus concentration in colonic contents and resulting in data gaps.2. Due to gut microbiota diversity and interactions, L. rhamnosus concentrations in some mouse samples deviated significantly from the mean after CaCO3 plate coating. Such erroneous data were excluded.Based on the above two points and preliminary experiments showed that approximately 25 % of mice could not be tested due to missing colonic contents after fasting. Therefore, 8 mice were included in the formal experiment as a reserve to ensure obtaining colonic contents from at least 6 mice. The final number of valid data points obtained per group ranged from 6 to 8: Obtaining only 6 points met the 3Rs principle for animal studies; Obtaining >6 points retained all valid data to respect facts. In the methods section, “n = 6” refers to the designed number of replicates. Variations in data points in the figures reflect the actual effective sample size. The authors would like to apologise for any inconvenience caused.
| Original language | English |
|---|---|
| Article number | 112430 |
| Journal | Food Hydrocolloids |
| Volume | 174 |
| DOIs |
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| State | Accepted/In press - 2026 |
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Dive into the research topics of 'Corrigendum to “Construction of walnut protein/tea polyphenol/alginate complex for enhancing heat and gastrointestinal tolerance of lactic acid bacteria” [Food Hydrocolloids 149 (2024) 109523] (Food Hydrocolloids (2024) 149, (S0268005X2301069X), (10.1016/j.foodhyd.2023.109523))'. Together they form a unique fingerprint.Cite this
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