@inproceedings{539e9c0e3fac4337a39e1197ecb5f927,
title = "Characterization of task-free/task-performance brain states",
abstract = "Both resting state fMRI (R-fMRI) and task-based fMRI (T-fMRI) have been widely used to study the functional activities of the human brain during task-free and task-performance periods, respectively. However, due to the difficulty in strictly controlling the participating subject{\textquoteright}s mental status and their cognitive behaviors during fMRI scans, it has been very challenging to tell whether or not an R-fMRI/T-fMRI scan truly reflects the participant{\textquoteright}s functional brain states in task-free/task-performance. This paper presents a novel approach to characterizing the brain{\textquoteright}s functional status into task-free or task-performance states. The basic idea here is that the brain{\textquoteright}s functional state is represented by a whole-brain quasi-stable connectivity pattern (WQCP), and an effective sparse coding procedure was then applied to learn the atomic connectivity patterns (ACP) of both task-free and task-performance states based on training R-fMRI and T-fMRI data. Our experimental results demonstrated that the learned ACPs for R-fMRI and T-fMRI datasets are substantially different, as expected. However, a certain portion of ACPs from R-fMRI and TfMRI datasets are overlapping, suggesting that those subjects with overlapping ACPs were not in the expected task-free/task-performance states during RfMRI/ T-fMRI scans.",
keywords = "Connectivity, Cortical landmarks, DTI, FMRI",
author = "Xin Zhang and Lei Guo and Xiang Li and Dajiang Zhu and Kaiming Li and Zhenqiang Sun and Changfeng Jin and Xintao Hu and Junwei Han and Qun Zhao and Lingjiang Li and Tianming Liu",
note = "Publisher Copyright: {\textcopyright} Springer-Verlag Berlin Heidelberg 2012.; 15th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2012 ; Conference date: 05-10-2012 Through 05-10-2012",
year = "2012",
doi = "10.1007/978-3-642-33418-4_30",
language = "英语",
isbn = "9783642334177",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "237--245",
editor = "Menze, {Bjoern H.} and Zhuowen Tu and Menze, {Bjoern H.} and Albert Montillo and Antonio Criminisi and Nicholas Ayache and Herv{\'e} Delingette and Le Lu and Georg Langs and Georg Langs and Polina Golland and Kensaku Mori",
booktitle = "Medical Image Computing and Computer-Assisted Intervention - MICCAI2012 - 15th International Conference, Proceedings",
}