CAUDA-MI: Cross Attention-Guided Unsupervised Domain Adaptation with Mutual Information for Cardiac MRI Segmentation

  • Dianrong Du
  • , Hengfei Cui
  • , Jiatong Li
  • , Fan Zheng
  • , Yong Xia

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Late Gadolinium Enhancement (LGE) imaging has emerged as the gold standard for cardiovascular disease diagnosis due to its ability to clearly delineate myocardial pathology. Professional interpretation of LGE images is usually difficult since their annotations are scarce, often necessitating the reliance on domain adaptation methods. Nevertheless, significant distribution discrepancy between datasets of different modalities usually results in poor transfer learning performances. To address this issue, we propose a general framework for cardiac MRI segmentation, called Cross Attention-Guided Unsupervised Domain Adaptation with Mutual Information (CAUDA-MI). This model leverages attention mechanisms on two data streams from the source and target domains, cleverly fusing the Query from the source domain with the Key and Value from the target domain, thereby aligning the implicit features of the target domain towards the source domain in the latent space. Additionally, we introduce single-domain mutual information as a supplementary means to further enhance the accuracy of myocardial segmentation. The proposed CAUDA-MI is tested on the MS-CMRSeg 2019 and MyoPS 2020 datasets, which achieves an average Dice score of 0.847 and 0.797 respectively. Comprehensive experimental results demonstrate that our proposed method surpasses previous state-of-the-art algorithms.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention, MICCAI 2025 - 28th International Conference, Proceedings
EditorsJames C. Gee, Jaesung Hong, Carole H. Sudre, Polina Golland, Daniel C. Alexander, Juan Eugenio Iglesias, Archana Venkataraman, Jong Hyo Kim
PublisherSpringer Science and Business Media Deutschland GmbH
Pages46-56
Number of pages11
ISBN (Print)9783032049773
DOIs
StatePublished - 2026
Event28th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2025 - Daejeon, Korea, Republic of
Duration: 23 Sep 202527 Sep 2025

Publication series

NameLecture Notes in Computer Science
Volume15965 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference28th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2025
Country/TerritoryKorea, Republic of
CityDaejeon
Period23/09/2527/09/25

Keywords

  • Cardiac segmentation
  • Domain adaptation

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