Carbon Cationic Relay via Superelectrophiles: Synthesis of Spiro-diazafluorenes

Dongqing Lin; Ying Wei; Changjin Ou; Hao Huang; Linghai Xie; Lei Tang; Wei Huang

doi:10.1021/acs.orglett.6b02595

Carbon Cationic Relay via Superelectrophiles: Synthesis of Spiro-diazafluorenes

Dongqing Lin
, Ying Wei
, Changjin Ou
, Hao Huang
, Linghai Xie
, Lei Tang
, Wei Huang

Nanjing University of Posts and Telecommunications
Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Superelectrophilic-initiated carbon cationic relay reactions of diazafluorenones with phenols were developed to provide strategically novel and atom-economic access to spirodiazafluorenes via tandem Friedel-Crafts reaction, nucleophilic addition, and intramolecular cyclization sequences. A range of spirodiazafluorenes that are difficult to synthesize with traditional protocols has been constructed successfully in middle to high yields using this method.

Original language	English
Pages (from-to)	6220-6223
Number of pages	4
Journal	Organic Letters
Volume	18
Issue number	24
DOIs	https://doi.org/10.1021/acs.orglett.6b02595
State	Published - 16 Dec 2016
Externally published	Yes

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title = "Carbon Cationic Relay via Superelectrophiles: Synthesis of Spiro-diazafluorenes",

abstract = "Superelectrophilic-initiated carbon cationic relay reactions of diazafluorenones with phenols were developed to provide strategically novel and atom-economic access to spirodiazafluorenes via tandem Friedel-Crafts reaction, nucleophilic addition, and intramolecular cyclization sequences. A range of spirodiazafluorenes that are difficult to synthesize with traditional protocols has been constructed successfully in middle to high yields using this method.",

author = "Dongqing Lin and Ying Wei and Changjin Ou and Hao Huang and Linghai Xie and Lei Tang and Wei Huang",

note = "Publisher Copyright: {\textcopyright} 2016 American Chemical Society.",

year = "2016",

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doi = "10.1021/acs.orglett.6b02595",

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T1 - Carbon Cationic Relay via Superelectrophiles

T2 - Synthesis of Spiro-diazafluorenes

AU - Lin, Dongqing

AU - Wei, Ying

AU - Ou, Changjin

AU - Huang, Hao

AU - Xie, Linghai

AU - Tang, Lei

AU - Huang, Wei

PY - 2016/12/16

Y1 - 2016/12/16

N2 - Superelectrophilic-initiated carbon cationic relay reactions of diazafluorenones with phenols were developed to provide strategically novel and atom-economic access to spirodiazafluorenes via tandem Friedel-Crafts reaction, nucleophilic addition, and intramolecular cyclization sequences. A range of spirodiazafluorenes that are difficult to synthesize with traditional protocols has been constructed successfully in middle to high yields using this method.

AB - Superelectrophilic-initiated carbon cationic relay reactions of diazafluorenones with phenols were developed to provide strategically novel and atom-economic access to spirodiazafluorenes via tandem Friedel-Crafts reaction, nucleophilic addition, and intramolecular cyclization sequences. A range of spirodiazafluorenes that are difficult to synthesize with traditional protocols has been constructed successfully in middle to high yields using this method.

UR - https://www.scopus.com/pages/publications/85006508409

U2 - 10.1021/acs.orglett.6b02595

DO - 10.1021/acs.orglett.6b02595

M3 - 文章

AN - SCOPUS:85006508409

SN - 1523-7060

VL - 18

SP - 6220

EP - 6223

JO - Organic Letters

JF - Organic Letters

IS - 24

ER -

Carbon Cationic Relay via Superelectrophiles: Synthesis of Spiro-diazafluorenes

Abstract

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